In this Article, we present a facile microwave-assisted synthesis route for the preparation of water-soluble and high-quality CuInS2/ZnS nanocrystals (NCs) with glutathione as the stabilizer. The as-prepared CuInS2/ZnS NCs exhibited small particle sizes (~3.3 nm), long photoluminescence lifetimes, and color-tunable properties ranging from the visible to the near-infrared by varying the initial ratio of Cu/In in the precursors. The low-toxicity, highly luminescent and biocompatible CuInS2/ZnS NCs were applied to cell imaging, showing that they could be used as promising fluorescent probes. Furthermore, the CuInS2/ZnS NCs were used as the signal labels for a fluoroimmunoassay of the biomarker IL-6, showing their great potential for use as reliable point-of-care diagnostics for biomarkers of cancer and other diseases.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/am402328t | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Microwave-Assisted Synthesis of Quasi-Pyramidal CuInS -ZnS Nanocrystals for Enhanced Near-Infrared Targeted Fluorescent Imaging of Subcutaneous Melanoma.
Adv Biosyst
January 2019
Stem Cell and Molecular Biology Laboratory, Bhupat and Jyoti Mehta School of Biosciences, Department of Biotechnology, Indian Institute of Technology-Madras (IIT-M), Chennai, 600036, India.
Near-infrared (NIR) fluorescent CuInS -ZnS nanocrystals (CIZS NCs) are synthesized via an ultra-fast, non-injection microwave (MW)-assisted nanoalloying process at 230 ºC within 5 min using 1-dodecanethiol (DDT) as both the sulfur source and solvent under solvothermal (ST) condition. The structural and surface analyses reveal that DDT-functionalized CIZS NCs exhibit quasi-pyramids of tetragonal-phase with well-defined facets. The DDT-functionalized CIZS NCs present a photoluminescence quantum yield (PLQY) of 76% and a long-lived fluorescence lifetime of ≈0.
View Article and Find Full Text PDFSustainable, Rapid Synthesis of Bright-Luminescent CuInS2-ZnS Alloyed Nanocrystals: Multistage Nano-xenotoxicity Assessment and Intravital Fluorescence Bioimaging in Zebrafish-Embryos.
Sci Rep
May 2016
Advanced Functional Nanostructured Materials Laboratory, Centre for Nanoscience and Technology, Madanjeet School of Green Energy Technologies, Pondicherry University, Kalapet, Puducherry-605014, India.
Near-infrared (NIR) luminescent CuInS2-ZnS alloyed nanocrystals (CIZS-NCs) for highly fluorescence bioimaging have received considerable interest in recent years. Owing, they became a desirable alternative to heavy-metal based-NCs and organic dyes with unique optical properties and low-toxicity for bioimaging and optoelectronic applications. In the present study, bright and robust CIZS-NCs have been synthesized within 5 min, as-high-as 230 °C without requiring any inert-gas atmosphere via microwave-solvothermal (MW-ST) method.
View Article and Find Full Text PDFBright, stable, and water-soluble CuInS2/ZnS nanocrystals passivated by cetyltrimethylammonium bromide.
Nanoscale Res Lett
April 2015
School of Mechanical Engineering, Korea University, 145 Anam-ro, Seoul, Korea.
We report a highly bright and stable aqueous dispersion of CuInS2/ZnS (CIS/ZnS) nanocrystals (NCs) using surfactant-assisted microemulsion and cold treatment. CIS/ZnS NCs were facilely synthesized via a stepwise, consecutive hybrid flow reactor approach. To stabilize the optical properties of hydrophobic CIS/ZnS NCs, cetyltrimethylammonium bromide (CTAB) was chosen as a matrix for aqueous phase transfer.
View Article and Find Full Text PDFLarge-scale synthesis of highly emissive and photostable CuInS2/ZnS nanocrystals through hybrid flow reactor.
Nanoscale Res Lett
February 2014
School of Mechanical Engineering, Korea University, Seoul, Korea.
We report a high-yield, low-cost synthesis route to colloidal CuInS2/ZnS (CIS/ZnS) nanocrystals (NCs) with Cu vacancies in the crystal lattice. Yellow-emitting CIS/ZnS core/shell NCs of high luminescence were facilely synthesized via a stepwise, consecutive hybrid flow reactor approach. It is based on serial combination of a batch-type mixer and a flow-type furnace.
View Article and Find Full Text PDFAqueous synthesis of color-tunable CuInS2/ZnS nanocrystals for the detection of human interleukin 6.
ACS Appl Mater Interfaces
August 2013
State Key Lab of Analytical Chemistry for Life Science, and School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, PR China.
In this Article, we present a facile microwave-assisted synthesis route for the preparation of water-soluble and high-quality CuInS2/ZnS nanocrystals (NCs) with glutathione as the stabilizer. The as-prepared CuInS2/ZnS NCs exhibited small particle sizes (~3.3 nm), long photoluminescence lifetimes, and color-tunable properties ranging from the visible to the near-infrared by varying the initial ratio of Cu/In in the precursors.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!