AI Article Synopsis
- Complete congenital heart block (CCHB) linked to neonatal lupus erythematosus is typically caused by maternal antibodies that affect the fetal heart, and it usually occurs before 30 weeks of pregnancy.
- An unusual case is presented where CCHB was identified after 32 weeks of gestation, which showed improvement in the heart condition post-delivery when treated with immunoglobulin.
- After birth, the baby's condition deteriorated due to a rise in heart rate, likely caused by immune system-related cardiomyopathy.
Article Abstract
Complete congenital heart block (CCHB) accompanied with neonatal lupus erythematosus is caused by an immune reaction between maternal anti-Ro/SSA antibodies and the fetal heart and is generally considered an irreversible process. This reaction mostly occurs before 30 weeks' gestation, especially between the 20th and 24th week. Reported here is an atypical case of neonatal lupus erythematosus with CCHB detected after 32 weeks' gestation that showed postnatal improvement in the degree of heart block after preterm delivery and immunoglobulin use. The clinical condition of the infant worsened with an increase in heart rate due to possible cardiomyopathy induced by the immune reaction.
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| http://dx.doi.org/10.1111/ped.12073 | DOI Listing |
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