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A glass half full of money: Dispositional optimism and wealth accumulation across the income spectrum.
J Pers Soc Psychol
January 2025
Marketing Division, Paul College of Business and Economics, University of New Hampshire.
What drives some people to save more effectively for their future than others? This multistudy investigation (N = 143,461) explores how dispositional optimism-the generalized tendency to hold positive expectations about the future-shapes individuals' financial decisions and outcomes. Leveraging both cross-sectional and longitudinal designs across several countries, our findings reveal that optimism significantly predicts greater savings over time, even when controlling for various demographic, psychological, and financial covariates. Furthermore, we find that the role of optimism varies based on socioeconomic circumstances: Among lower income individuals, optimism is more strongly associated with saving.
View Article and Find Full Text PDFExercising Self-Control Increases Responsivity to Hedonic and Eudaimonic Rewards.
Soc Cogn Affect Neurosci
January 2025
Centre for Research on Self and Identity, School of Psychology, University of Southampton, United Kingdom.
The reward responsivity hypothesis of self-control proposes that, irrespective of self-control success, exercising self-control is aversive and engenders negative affect. To countermand this discomfort, reward-seeking behavior may be amplified after bouts of self-control, bringing individuals back to a mildly positive baseline state. Previous studies indicated that effort-an integral component of self-control-can increase reward responsivity.
View Article and Find Full Text PDFSuperloaded Multiplexed scRNA-seq Data Preserves Primary Immune Cell Heterogeneity but Necessitates Stringent Doublet Removal.
Immunol Invest
January 2025
Transplantation Research Institute, Seoul National University Medical Research Center, Seoul, South Korea.
Background: Single-cell RNA sequencing (scRNA-seq) has improved our ability to characterize rare cell populations. In practice, cells from different tissues or donors are simultaneously loaded onto the instrument (multiplexed) at the recommended (standard loading) or higher (superloading) numbers to save time and money. Although cost-effective, superloading can stymie computational analyses owing to high multiplet rates and sample complexity.
View Article and Find Full Text PDFBiophysics-guided uncertainty-aware deep learning uncovers high-affinity plastic-binding peptides.
Digit Discov
January 2025
Department of Chemical and Biomolecular Engineering, North Carolina State University Raleigh North Carolina 27606 USA
Plastic pollution, particularly microplastics (MPs), poses a significant global threat to ecosystems and human health, necessitating innovative remediation strategies. Biocompatible and biodegradable plastic-binding peptides (PBPs) offer a potential solution through targeted adsorption and subsequent MP detection or removal from the environment. A challenge in discovering plastic-binding peptides is the vast combinatorial space of possible peptides (, over 10 for 12-mer peptides), which far exceeds the sample sizes typically reachable by experiments or biophysics-based computational methods.
View Article and Find Full Text PDFBudget impact analyses of hemoglobin A1c and lipid panel point-of-care testing with Afinion™ 2 in Canada and Italy.
J Comp Eff Res
January 2025
Abbott Rapid Diagnostics, 110 Viale Thomas Alva Edison, Sesto San Giovanni, MI, Italy, 2009.
Screening and monitoring of diabetes or dyslipidemia frequently involves a multi-step process requiring patients to obtain test requisitions from their primary care physician (PCP), followed by a laboratory visit and re-consultation. Point-of-care testing (POCT) for hemoglobin A (HbA) and lipid panel can streamline the patient care pathway. This study assessed the budget impact of introducing Afinion™ 2 POCT (Abbott Rapid Diagnostics) from the Canadian and Italian societal perspectives.
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