Primary ovarian lymphoma is very rare. Ovarian involvement by non-Hodgkin's lymphoma is usually secondary, occurring as part of a systemic disease. We report a case of primary diffuse large B-cell lymphoma of the ovary manifesting as advanced ovarian cancer. The diagnosis was confirmed on histological and immunohistochemical analysis. The patient was treated with surgery followed by chemotherapy using rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) regimen.
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