The usefulness of isotope lymphography was evaluated in patients with chronic lower leg swelling. Forty patients (15 male, 25 female, age range 5 months-67 years) were assigned one of six clinical diagnoses based on clinical assessments, venography and lymphography. All the patients and seven normal controls were examined with bilateral isotope lymphography involving subcutaneous injection of 0.15 ml 99mTc-antimony sulphide colloid into the first web space of each foot. The percentage uptake of isotope-colloid in the inguinal lymph nodes at 1 and 2 h was equated with lymphatic function. Highly significant (P = 0.0001) differences existed between the different clinical groups and isotope lymphography discriminated well between oedema of lymphatic and non-lymphatic origin. Isotope lymphography appears to be a safe and useful test of lymphatic function.
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http://dx.doi.org/10.1111/j.1365-2133.1990.tb01821.x | DOI Listing |
J Plast Reconstr Aesthet Surg
December 2024
Lymphedema Clinic Tokyo, Tokyo, Japan. Electronic address:
Background: The management of lymphatic vesicles is challenging. This study aimed to clarify the lymphatic flow around the genitals and assess the effect of genital lymphaticovenous anastomosis (LVA) on lymphatic vesicles.
Methods: We conducted a retrospective study of 34 patients who underwent lymphatic vesicle resection and LVA.
Medicina (Kaunas)
November 2023
The Royal Wolverhampton NHS Trust, Wolverhampton WV10 0QP, UK.
: This review paper highlights the key alternatives to the blue dye/radioisotope method of sentinel lymph node biopsy (SLNB). It analyses the research available on these alternative methods and their outcomes compared to the traditional techniques. : This review focused on fifteen articles, of which five used indocyanine green (ICG) as a tracer, four used magnetic tracers, one used one-step nucleic acid amplification (OSNA) and Metasin (quantitative reverse transcriptase-polymerase chain reaction), one used the photosensitiser talaporfin sodium, one used sulphur hexafluoride gas microbubbles, one used CT-guided lymphography and two focused on general SLNB technique reviews.
View Article and Find Full Text PDFMicrosurgery
January 2024
Department of Surgery, Oncology Division, Faculty of Medicine, Universitas Indonesia - Dr Cipto Mangunkusumo General Hospital, Jakarta, Indonesia.
Approximately 60%-70% of breast cancer patients in Indonesia are diagnosed in the locally advanced stage. The stage carries a higher risk of lymph node metastasis which increases susceptibility to lymph obstruction. Hence, breast cancer-related lymphedema (BCRL) could present before axillary lymph node dissection (ALND).
View Article and Find Full Text PDFJ Clin Ultrasound
March 2022
Department of Ultrasonography, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Sentinel lymph node biopsy has been regarded as the standard procedure for early staging breast cancer. One of the key steps is to locate the sentinel lymph node (SLN). The recommended method is the joint use of blue dye and radioisotope.
View Article and Find Full Text PDFCancers (Basel)
August 2021
Department of Surgical Sciences, Uppsala University, 75185 Uppsala, Sweden.
Lymph Node Dissection (SLND) is standard of care for diagnosing sentinel lymph node (SLN) status in patients with early breast cancer. Study aim was to determine whether the combination of Superparamagnetic iron oxide nanoparticles (SPIO) MRI-lymphography (MRI-LG) and a Magnetic-guided Axillary UltraSound (MagUS) with biopsy can allow for minimally invasive, axillary evaluation to de-escalate surgery. Patients were injected with 2 mL of SPIO and underwent MRI-LG for SN mapping.
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