Inactive in the membrane: Lipidated light-responsive constructs that sequester bioagents (R, see scheme) to the membranes of organelles and cells have been constructed. When membrane-bound, the bioagent is not susceptible to processing by its biological target. Photolysis releases the bioagent from its membrane anchor and thereby renders it biologically active.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840492 | PMC |
| http://dx.doi.org/10.1002/anie.201305510 | DOI Listing |
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