Objectives: Evidence about the health and quality-of-life outcomes of injuries is obtained mainly from follow-up studies of surviving trauma patients; population-based studies are rarer, in particular for countries in Eastern Europe. This study examines the incidence, prevalence and social variation in non-fatal injuries resulting in activity limitations and outcomes of injuries in Estonia.
Design: A retrospective population-based study.
Setting: Estonia.
Participants: 7855 respondents of the face-to-face interviews of the second round of the Estonian Family and Fertility Survey conducted between 2004 and 2005 based on the nationally representative probability sample (n=11 192) of the resident population of Estonia aged 20-79.
Primary And Secondary Outcome Measures: The cumulative incidence and prevalence of injuries leading to activity limitations was estimated. Survival models were applied to analyse variations in the injury risk across sociodemographic groups. The association between injuries and the development of chronic conditions and quality of life was examined using survival and logistic regression models.
Results: 10% (95% CI 9.4 to 10.7) of the population aged 20-79 had experienced injuries leading to activity limitations; the prevalence of activity limitations due to injuries was 4.4% (95% CI 3.9% to 4.9%). Significant differences in injury risk were associated with gender, education, employment, marital status and nativity. Limiting injury was associated with a doubling of the likelihood of having chronic conditions (adjusted HR 1.97, 95% CI 1.58 to 2.46). Injury exhibited a statistically significant negative association with most quality-of-life measures. Although reduced, these effects persisted after recovery from activity limitations.
Conclusions: Substantial variation in injury risk across population groups suggests potential for prevention. Men and workers in manual occupations constitute major target groups for injury prevention in Estonia. The association of injury with the development of chronic conditions and reduced quality of life warrants further investigation.
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http://dx.doi.org/10.1136/bmjopen-2013-002695 | DOI Listing |
ACS Appl Mater Interfaces
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Department of Radiology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, No. 651 Dongfeng Road East, Guangzhou, Guangdong 510060, P. R. China.
The clinical application of tyrosine kinase inhibitors (TKIs) is rapidly growing and has emerged as a cornerstone in the treatment of both solid tumors and hematologic malignancies. However, resistance to TKI targets and disease progression remain inevitable. Nanocarrier-mediated delivery has emerged as a promising strategy to overcome the limitations of the TKI application.
View Article and Find Full Text PDFJMIR Form Res
January 2025
CIRCLE - Complex Intervention Research in Health and Care, Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Background: Parents of children treated for cancer may experience psychological difficulties including depression, anxiety, and posttraumatic stress. Digital interventions, such as internet-administered cognitive behavioral therapy, offer an accessible and flexible means to support parents. However, engagement with and adherence to digital interventions remain a significant challenge, potentially limiting efficacy.
View Article and Find Full Text PDFPurpose: To determine the status of depression and its key influencing factors among Chinese older adults in different living situations.
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Acta Bioeng Biomech
June 2024
1Faculty of Sports Science, Ningbo University, Ningbo, China.
: The impact of shoe stiffness on running biomechanics is well-documented, while the specific effect on the performance of biomechanically distinct groups such as novice runners and experienced runners is still largely unexplored. The study aimed to evaluate the biomechanical effect of different shoe longitudinal bending stiffness on the lower limb during running in novice runners and experienced runners. : Twelve experienced runners and ten novice runners ran at a speed of 4.
View Article and Find Full Text PDFUrol Pract
November 2024
Department of Urology, Mayo Clinic, Rochester, Minnesota.
Introduction: The limitations of lectures are magnified when teaching technical skills. A "flipped classroom" (FC) model allows learners to first review material and replaces lectures with active teacher-learner engagement. FC has been shown to improve knowledge retention, but its impact on skill acquisition is unknown.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!