Introduction: Trauma is a major cause of death worldwide, mainly affecting a young male population. Blunt trauma of the abdomen can cause a trauma of the mesentery in 5 % of cases. Rapid decelerations and injuries by seat belts are the most common pathophysiological mechanisms. Three-dimensional anatomical scanning of the mesentery and gastrointestinal tract is the first essential step in modeling abdominal trauma in an attempt to understand the pathophysiology of mesenteric lesions and to improve the safety features of vehicles.
Objective Of The Study: To analyze the individual variability of the mesentery and the superior mesenteric artery (SMA) from medical imaging and to develop a three-dimensional customizable finite element model.
Materials And Methods: In this retrospective study, one hundred abdominopelvic injected CT scans were analyzed from healthy patients. The evaluation criteria of the mesentery were its volume (total and the distribution of adipose tissue/non adipose tissue), the length of the SMA and the distance between duodenojejunal angle (DJA) and the ileocecal junction (ICJ). The variability of these measures has been studied by demographic (age and gender) and morphologic (height evaluated by the T11-L4 distance, the waist circumference and the thickness of the subcutaneous adipose tissue).
Results: Mean mesenteric volume was 644 cm(3) (ranges from 89 to 1,869 cm(3)), and the mean length of the SMA was 224.9 mm (ranges from 138.4 to 312.3). There was a statistically significant association between waist circumference and the total volume of the mesentery, its fat component and non fat component (p < 0.001). Waist circumference was the only morphological parameter associated with the length of the superior mesenteric artery and the length of the DJA to ICJ (p < 0.001). Subcutaneous adipose tissue and female sex were statistically associated with total mesentery volume (respectively, p = 0.005 and p = 0.001). Age was an independent predictor of the increased volume of the mesentery and the length of the SMA. The height of the subject changes the length of the SMA (p = 0.001).
Conclusion: The assessment of the mesenteric variability highlighted three factors associated with its size and length: age, sex, and waist circumference. These parameters have to be taken into account to personalize numerical model in the area of virtual trauma.
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http://dx.doi.org/10.1007/s00276-013-1178-1 | DOI Listing |
Zhonghua Wei Chang Wai Ke Za Zhi
December 2024
Department of General Surgery, the Second Affiliated Hospital, Zhengzhou University, Zhengzhou450014, China.
To investigate and compare the clinical efficacy and prognosis of D3 lymphadenectomy/complete mesocolic excision in treatment of right colon cancer with different medial boundaries. We searched The Cochrane Library, Pubmed, Embase, CBM, VIP, CNKI, and WanFang data bases for superior mesenteric artery (SMA)-oriented and superior mesenteric vein (SMV)-oriented D3 lymphadenectomy/complete mesocolic excision from inception to December, 2023. The resultant data were submitted to meta-analysis using RevMan 5.
View Article and Find Full Text PDFAbdom Radiol (NY)
December 2024
Department of Critical Care Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
Purpose: The trend of muscle wasting in patients with acute severe and moderately severe pancreatitis (AP) remains unclear. This retrospective study aimed to investigate the trend of skeletal muscle area (SMA) changes and its impact on patients with severe and moderately severe AP.
Methods: Patients diagnosed with AP who had repeated CT scans after intensive care unit (ICU) admission were included.
Mol Med
December 2024
Orthopedics Department, The Third Xiangya Hospital of Central South University, No.138 Tongzipo Road, Yuelu District, Changsha, 410013, China.
Background: Rotator cuff tears (RCTs) are among the most common musculoskeletal disorders that affect quality of life. This study aimed to investigate the efficacy of ginsenoside Rb1 in RCTs and the mechanisms involved.
Methods: First, a fibrotic model of FAPs was induced, and FAPs were cultured in media supplemented with different concentrations of ginsenoside Rb1.
J Psychiatr Res
November 2024
Neuropsychiatry Imaging Center, Department of Radiology, Shenzhen Kangning Hospital, Shenzhen Mental Health Center, Shenzhen, Guangdong, 518020, China. Electronic address:
Background: Recurrent major depressive disorder (RDD) is increasingly understood to be associated with a 'disconnection' within the brain areas. But, the true understanding of cortical connectivities remains challenging. Morphometric similarity network (MSN) with multi-modal magnetic resonance imaging (MRI) could provide more information about cortical micro-architecture changes in individuals with RDD.
View Article and Find Full Text PDFBioorg Chem
November 2024
Department of Zoology, Mahila Mahavidyalaya, Banaras Hindu University, Varanasi 221005, India. Electronic address:
The alveolar epithelium is a crucial barrier against external threats, yet it becomes a key player in initiating pulmonary fibrosis when compromised. Despite its importance, the intricate relationship between, DBP exposure and alveolar epithelial cell injury ensuing pro-fibrotic effects remains poorly understood. Phthalates, ubiquitous in nature, pose a significant risk to lung health upon inhalation, acting as immune triggers that cause airway inflammation and epithelial damage.
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