AI Article Synopsis
- Panniculitides include various conditions affecting the subcutaneous tissue, with a focus on identifying vasculitis through histopathology.
- The main differential diagnoses are polyarteritis nodosa (PAN), nodular vasculitis (NV), and Bazin's erythema induratum (EI), with PAN requiring long-term monitoring due to potential systemic progression.
- NV and EI are the most common types of lobular panniculitis with vasculitis, and it's important to differentiate them based on NV positive skin test results equating to EI, while other rare types are linked to systemic conditions like infections or autoimmune disorders.
Article Abstract
Panniculitides encompass a great number of different entities; however, once a vasculitis has been detected histopathologically within the subcutaneous tissue, the differential diagnosis is mainly restricted to polyarteritis (panarteritis) nodosa (PAN), nodular vasculitis (NV), and Bazin's erythema induratum (EI). Patients with PAN may have the disease confined to the skin, but must be followed over a long period because many of them develop late systemic disease. The NV/EI group represents by far the most common type of lobular panniculitis with vasculitis; we prefer keeping the distinction between the two entities by underlining the equation NV positive tuberculin skin test = EI. Other lobular panniculitides with vasculitis are exceedingly rare and set in a systemic background which can be infectious (lepromatous leprosy panniculitides) or autoimmune/dysreactive (neutrophilic lobular panniculitis in rheumatoid arthritis, lobular panniculitis in inflammatory bowel disease).
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!