Nucleic acid amplification testing (NAAT) is increasingly being adopted for diagnosis of Clostridium difficile infection (CDI). Data from 3 states conducting population-based CDI surveillance showed increases ranging from 43% to 67% in CDI incidence attributable to changing from toxin enzyme immunoassays to NAAT. CDI surveillance requires adjustment for testing methods.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9580544PMC
http://dx.doi.org/10.1093/cid/cit492DOI Listing

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