The aim of this study was to determine whether a postoperative stay of 3 hours is warranted for patients with obstructive sleep apnea (OSA). The secondary focus was to examine those patients who left against medical advice without complications. This retrospective chart review examined adult patients with previously diagnosed sleep apnea treated with pressure-emitting machines that underwent outpatient procedures with moderate sedation. The 369-bed community hospital where the study took place had the practice of recovering OSA patients for a 3-hour period. Data were collected to compare presedation oxygen, postsedation oxygen, and length of stay in minutes. Additional data collected from all patients included age, gender, weight, reversal medications, if required, and Aldrete score. Of the 118 subjects, there were no statistical differences noted in oxygenation scores before and after procedure yet the clinical improvement is noteworthy. Many of the subjects (n = 92) left against medical advice before the 3-hour period. In conclusion, a 3-hour time period may be too long for outpatients with OSA requiring machine assistance who undergo a procedure with moderate sedation.
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http://dx.doi.org/10.1097/SGA.0b013e31829c6c45 | DOI Listing |
Epilepsia
January 2025
Epilepsy Unit, Hôpital Gui de Chauliac, Montpellier, France.
Contemporary studies report nonconvulsive status epilepticus (NCSE) in Creutzfeldt-Jakob disease (CJD), based on benzodiazepine (BZP)-responsive epileptiform discharges on the electroencephalogram (EEG), with the following false syllogism: (1) intravenous (IV) administration of BZPs usually suppress ictal activity in NCSE; (2) in CJD, periodic sharp wave complexes (PSWCs) are suppressed by IV BZPs; (3) therefore, these patients have NCSE. This is a simplistic and invalid conclusion, because authors of 20th-century science reports have clearly shown that IV BZPs, short-acting barbiturates, and drugs with no antiseizure effects, such as chloral hydrate and IV naloxone, suppress PSWCs, but patients fall asleep with no clinical improvement. In contrast, IV methylphenidate transiently improves both the EEG and clinical states.
View Article and Find Full Text PDFAnn Otol Rhinol Laryngol
January 2025
School of Clinical Medicine, Women's Health Paediatrics and Child Health, University of New South Wales, Sydney, NSW, Australia.
Objectives: The prevalence of obstructive sleep apnea (OSA) is known to be higher in children with Down syndrome (DS) than the general pediatric population, with lower rates of surgical cure. This study aims to determine the prevalence and predictors of OSA and evaluate the outcomes of surgical intervention for OSA in a cohort of Australian children with DS.
Methodology: A retrospective chart review was conducted on 156 patients with DS from 0 to 18 years who had undergone overnight, attended polysomnography (PSG) at Sydney Children's Hospital from January 2010 to July 2023.
BMC Musculoskelet Disord
January 2025
Department of Internal Medicine, Division of Rheumatology, Soonchunhyang University Seoul Hospital, Soonchunhyang University School of Medicine, Seoul, South Korea.
Background: Obstructive sleep apnea (OSA) is linked to various health conditions, including cardiovascular diseases and metabolic disorders. Hyperuricemia and gout may be associated with OSA, but large-scale studies on this are limited. This study aimed to investigate the association between hyperuricemia/gout and OSA using data from the Korea National Health and Nutrition Survey (KNHANES).
View Article and Find Full Text PDFSleep Breath
January 2025
Clinical Internal Medicine Department, Shanghai Health and Medical Center, Wuxi, 214065, People's Republic of China.
Background: Obstructive sleep apnea has been associated with various urinary system diseases, including prostatic hyperplasia and nocturia. Recently, it has been linked to prostate cancer. This study investigated the relationship between the apnea hypopnea index, prostate-specific antigen (PSA) levels, and changes in PSA.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
GloNeuro Academy, Noida, Uttar Pradesh, India.
Background: Obesity is caused by the buildup of excess body fat, which upsets homeostasis. Genetic, epigenetic, and behavioural variables all have a role in the pathophysiology of obesity. In turn, obesity throws off the sleep cycle, leading to sleep problems.
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