The aim of this study was to compare the effect of a cycling training programme performed at intensity corresponding to the lowest value of the respiratory quotient (RQ) versus at intensity corresponding to the ventilatory threshold (VT), on body composition and health-related parameters in overweight women. Thirty-two sedentary obese women (27-42 years old) were studied in a randomized trial of either RQ (n = 17) or VT (n = 15). RQ and VT training sessions were equalized by time (60 min) and performed in a cycloergometer. Anthropometry, body composition, lipid profile, glucose, basal metabolic rate (BMR) and fitness (maximal oxygen uptake) were evaluated before and after 12 weeks of intervention. Body weight, body mass index, fatness and fitness were improved in both groups (P<0·001). Triglycerides (TG) levels decreased only in response to RQ (P<0·001) and fat-free mass (FFM) to VT (P = 0·002). No differences were observed between groups. Both exercise intensities seem to be effective for improving health in overweight women. However, low-intensity compared with the high-intensity exercise training appears to have additional benefits on TG levels and to maintenance of FFM.
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http://dx.doi.org/10.1111/cpf.12076 | DOI Listing |
BMJ Open
January 2025
National Institute of Health and Care Research (NIHR) Birmingham Biomedical Research Centre (BRC) Center for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, England, UK
Introduction: Primary sclerosing cholangitis (PSC) is the classical hepatobiliary manifestation of inflammatory bowel disease (IBD). The strong association between gut and liver inflammation has driven several pathogenic hypotheses to which the intestinal microbiome is proposed to contribute. Pilot studies of faecal microbiota transplantation (FMT) in PSC and IBD are demonstrated to be safe and associated with increased gut bacterial diversity.
View Article and Find Full Text PDFBackground: Adaptation of the right ventricle is a key determinant of outcomes in pulmonary arterial hypertension (PAH). Despite a compelling rationale to develop targeted therapies for the right ventricle in PAH, no such treatments exist. H-receptor antagonism is a potential myocardial-focused paradigm in heart failure.
View Article and Find Full Text PDFClin Spine Surg
January 2025
Department of Orthopedic Surgery, NYU Langone Health, New York, NY.
Study Design: Retrospective cohort study.
Objective: To develop parameter thresholds obtainable from cervical radiographs that correlate with concomitant thoracolumbar malalignment.
Summary Of Background Data: T1 slope (T1S) is typically discussed in the context of cervical deformity and correlated with health-related quality of life outcomes.
Disabil Rehabil
January 2025
Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Kutahya Health Sciences University, Kutahya, Türkiye.
Purpose: This study aimed to investigate the effectiveness of Manual Lymphatic Drainage (MLD) on the pain intensity, impact of the disease, and health-related quality of life among women diagnosed with Fibromyalgia syndrome (FMS).
Methods: The study was designed as a single-center, double-blind, randomized, and sham-controlled trial. Twenty women with FMS were included and randomized into intervention ( = 11) and sham control ( = 9) groups.
JMIR Infodemiology
January 2025
Ankara Etlik City Hospital, Ankara, TR.
Background: YouTube is an increasingly used platform for medical information. However, the reliability and validity of health-related information on celiac disease (CD) on YouTube has not been determined.
Objective: The aim of this study was to analyse the reliability and validity of CD-related YouTube videos.
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