Mucous membranes of human respiratory, digestive, and urinary systems of man were studied using histological methods in the autopsy material obtained from 60 persons of both sexes in the age range from the newborn period to the senescent age. It was shown that in addition to the interepithelial lymphocytes of the surface epithelium and lymphoid nodules, cells of the lymphoid series formed a continuous subepithelial layer (upper part of the esophagus, trachea), clusters of lymphocytes and plasma cells were found in the stroma of the tracheal glands, around excretory ducts (lymphocytic sheaths), lymphocytes were also observed in the intestinal crypts. The comparative characteristic of the structure of the mucous membranes of various organs is given.

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