Filling positions: 7-Azaindoles are important targets in the pharmaceutical industry. All five carbon positions of the azaindole ring system can be functionalized in a predictable manner starting from the appropriately substituted azaindole 1 by directed metalation and halogen/magnesium and sulfoxide/magnesium exchange. The products are fully substituted azaindoles of type 2.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/anie.201303490 | DOI Listing |
Publication Analysis
Top Keywords
sulfoxide/magnesium exchange
8
full functionalization
4
functionalization 7-azaindole
4
7-azaindole scaffold
4
scaffold selective
4
selective metalation
4
metalation sulfoxide/magnesium
4
exchange filling
4
filling positions
4
positions 7-azaindoles
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!