Introduction: Nerve deformation affects physiological function. Bands of Fontana are an optical manifestation of axonal undulations and may provide a structural indicator of nerve strain.
Methods: We developed an automated Fourier-based image processing method to quantify the periodicity of bands of Fontana both in bright field images and in axonal undulations in immunolabeled longitudinal sections.
Results: We found a strong linear relationship between applied strain and the frequency of bands of Fontana in rat sciatic nerves (-0.0056 μm(-) ⋅%(-) , r2 = 0.829; P < 0.05). This relationship agreed with the observed trend between strain and axonal waviness, calculated from longitudinal sections of sciatic nerves immunolabeled against myelin basic protein.
Conclusions: This accurate and objective approach has potential to increase our understanding of structure-function relationships in the nervous system and to guide preservation and enhancement of neural function.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/mus.23809 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Axis dependent conduction polarity in the air-stable semiconductor, PdSe.
Mater Horiz
August 2023
Dept of Chemistry and Biochemistry, The Ohio State University, 100 W. 18th Ave., Columbus, OH 43210, USA.
Axis-dependent conduction polarity (ADCP) is a unique electronic phenomena in which the charge polarity of carrier conduction can differ from p-type to n-type depending on the direction of travel through the crystal. Most materials that exhibit ADCP are metals, and very few semiconducting materials exhibit this effect. Here, we establish that PdSe, a ∼0.
View Article and Find Full Text PDFQuantification of the Number of Steps in a School Recess by Means of Smart Bands: Proposal of Referential Values for Children and Adolescents.
Children (Basel)
May 2023
Carrera de Ciencias de la Actividad Física y del Deporte, Facultad de Ciencias de la Salud, Universidad San Ignacio de Loyola, Av. La Fontana 550, La Molina, Lima 15024, Peru.
(1) Background: Regular physical activity has multiple benefits. Therefore, school recess is a key tool to provide opportunities for schoolchildren to engage in extracurricular physical activity, have fun, play and interact with their peers. The aim is to provide reference data to quantify the number of steps that children and adolescents perform in a school recess using smart bands according to age range and sex.
View Article and Find Full Text PDFActuator and Contact Force Modeling of an Active Soft Brace for Scoliosis.
Bioengineering (Basel)
July 2022
Institute of Mechanical Intelligence, Scuola Superiore Sant'Anna, 56010 Pisa, Italy.
Scoliosis is an abnormality of the spinal curvature that severely affects the musculoskeletal, respiratory, and nervous systems. Conventionally, it is treated using rigid spinal braces. These braces are static, rigid, and passive in nature, and they (largely) limit the mobility of the spine, resulting in other spinal complexities.
View Article and Find Full Text PDFApplications of Heterogeneous Photocatalysis to the Degradation of Oxytetracycline in Water: A Review.
Molecules
April 2022
INSTM and Department of Engineering and Applied Sciences, University of Bergamo, 24044 Dalmine, Italy.
Photocatalytic processes are being studied extensively as potential advanced wastewater treatments for the removal of pharmaceuticals, pesticides and other recalcitrant micropollutants from the effluents of conventional wastewater treatment plants (WWTPs). Oxytetracycline (OTC) is a widespread antibiotic which is frequently detected in surface water bodies as a recalcitrant and persistent micropollutant. This review provides an update on advances in heterogeneous photocatalysis for the degradation of OTC in water under UV light, sunlight and visible-light irradiation.
View Article and Find Full Text PDFChitosan-Based Biomaterial, Calcium Hydroxide and Chlorhexidine for Potential Use as Intracanal Medication.
Materials (Basel)
January 2021
Instituto de Pesquisas, Endodontia, São Leopoldo Mandic, Faculdade São Leopoldo Mandic, Rua Dr. José Rocha Junqueira, 13, Ponte Preta, Campinas 13045-755, SP, Brazil.
Article Synopsis
- The study aimed to create a chitosan-based biomaterial with calcium hydroxide and chlorhexidine to reduce microorganisms in root canals.
- Chitosan was prepared by dissolving it in acetic acid, and different samples were created using varying concentrations of the materials, which were then characterized using techniques like FTIR and XRD.
- The results showed that the new formulation demonstrated strong antimicrobial activity, particularly in samples containing chlorhexidine, suggesting its potential use as an effective intracanal treatment.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!