Chronic hepatitis C therapy: a rare complication revisited.

BMJ Case Rep

Department of Medicine, University Hospital, Case Western Reserve, Cleveland, Ohio, USA.

Published: July 2013

AI Article Synopsis

  • The combined therapy of peg-interferon α2a and ribavirin with protease inhibitors (boceprevir or telaprevir) is an effective treatment for hepatitis C.
  • A 50-year-old man developed insulin-dependent diabetes shortly after starting this triple therapy.
  • As a result of this rare side effect, his treatment had to be halted, complicating his hepatitis C infection management.

Article Abstract

The combined regimen of peg-interferon α2a plus ribavirin along with protease inhibitors (boceprevir or telaprevir) is considered as a very portent and effective therapy for hepatitis C infections. However, this combined therapy has been associated with a side effect that can make the course of the disease more complicated. In this case, a 50-year-old man developed insulin-dependent diabetes soon after initiating triple hepatitis C therapy. The treatment had to be stopped and the course of his hepatitis C infection has been challenged with this rare side effect.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736303PMC
http://dx.doi.org/10.1136/bcr-2013-200514DOI Listing

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