Synthesis of ZnO nanoparticles and evaluation of antioxidant and cytotoxic activity.

Colloids Surf B Biointerfaces

Department of Chemical Sciences, India. Electronic address:

Published: November 2013

ZnO nanoparticles were synthesized by thermal decomposition method and were characterized by UV-vis spectroscopy, XRD, SEM, EDX and TEM analysis. The resultant nanoparticles are nearly spherical and size is in the range of 40-50 nm. The antioxidant behavior of ZnO nanoparticles was assessed by scavenging free radicals of 2,2-diphenyl-1-picrylhydrazyl hydrate (DPPH) with varying nanoparticle concentration and time interval individually. The DPPH scavenging activity was monitored by UV-vis spectrophotometer. ZnO nanoparticles were also showing cytotoxic activity which was studied by hemolytic potentiality test.

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http://dx.doi.org/10.1016/j.colsurfb.2013.06.041DOI Listing

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