AI Article Synopsis

  • * Excessive body fat can lead to dyslipidemia, which increases the risk of heart disease; thus, understanding this relationship is essential for lipid specialists.
  • * A 2012 National Lipid Association conference focused on the impact of body fat on lipoproteins and discussed ways to manage dyslipidemia through diet, exercise, medications, and surgery to improve cardiovascular health in overweight individuals.

Article Abstract

The term "fat" may refer to lipids as well as the cells and tissue that store lipid (ie, adipocytes and adipose tissue). "Lipid" is derived from "lipos," which refers to animal fat or vegetable oil. Adiposity refers to body fat and is derived from "adipo," referring to fat. Adipocytes and adipose tissue store the greatest amount of body lipids, including triglycerides and free cholesterol. Adipocytes and adipose tissue are active from an endocrine and immune standpoint. Adipocyte hypertrophy and excessive adipose tissue accumulation can promote pathogenic adipocyte and adipose tissue effects (adiposopathy), resulting in abnormal levels of circulating lipids, with dyslipidemia being a major atherosclerotic coronary heart disease risk factor. It is therefore incumbent upon lipidologists to be among the most knowledgeable in the understanding of the relationship between excessive body fat and dyslipidemia. On September 16, 2012, the National Lipid Association held a Consensus Conference with the goal of better defining the effect of adiposity on lipoproteins, how the pathos of excessive body fat (adiposopathy) contributes to dyslipidemia, and how therapies such as appropriate nutrition, increased physical activity, weight-management drugs, and bariatric surgery might be expected to impact dyslipidemia. It is hoped that the information derived from these proceedings will promote a greater appreciation among clinicians of the impact of excess adiposity and its treatment on dyslipidemia and prompt more research on the effects of interventions for improving dyslipidemia and reducing cardiovascular disease risk in overweight and obese patients.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacl.2013.04.001DOI Listing

Publication Analysis

Top Keywords

adipose tissue
20
adipocytes adipose
12
body fat
12
national lipid
8
lipid association
8
tissue store
8
disease risk
8
excessive body
8
dyslipidemia
7
tissue
6

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!