A number of clinical cases of inflammatory changes in the nasopharynx rhinosinusitis apply to the area of auditory tube with the development of exudative otitis media. The objective of the present simple open study was to estimate the effectiveness and safety of the treatment of moderately severe acute rhinosinusitis associated with exudative otitis media in the children and adolescents with the use of sinuforte as starting monotherapy. The study included 47 patients at the age from 7 to 15 years. The results obtained indicate that the effectiveness of this treatment is comparable in terms of duration with that of traditional therapy. However, the use of sinuforte as initial monotherapy has some advantages over the traditional modality in that it reduces the drug loading and offers a simple scheme of the treatment with proven safety. Taken together, these advantages provide a conclusive argument in favour of selecting Sinuforte as initial therapy of the above ENT pathology.

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