Influence of reamberin on dynamics of functional condition of mitogen-induced immunocompetent blood cells at patients with widespread purulent peritonitis is studied. It is established that investigated immunocompetent cells have regulating effect on migration of neutrophil leukocytes at widespread purulent peritonitis during all postoperative period. PHA-activated mononuclear cells don't cause inhibition of migration of neutrophil granulocytes, observed in norm. At the same time the LPS-activated monocytes lead to migration strengthening of neutrophil granulocytes, in comparison with the data received in norm. Usage of reamberin at patients with widespread purulent peritonitis renders corrective action on immunocompetent cells, changing their properties of regulation of migratory activity of neutrophil granulocytes. The revealed effects at use of reamberin most expressed by the 7-10th days of the postoperative period.
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Surg Neurol Int
November 2024
Faculty of Dental Medicine and Health Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia.
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Biomedicines
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Toxicology and Pharmacology Laboratory, National Center for Biotechnology, Astana 010000, Kazakhstan.
Chronic wounds complicated by infection pose significant clinical challenges, necessitating comprehensive treatment approaches. The widespread use of antibiotics has led to resistant microorganisms, complicating traditional therapies. This study aims to develop and evaluate modified alginate wound dressings with enhanced antimicrobial and regenerative properties.
View Article and Find Full Text PDFAnimals (Basel)
September 2024
Clinic Unit for Poultry Medicine, Clinical Center for Population Medicine in Fish, Pigs, and Poultry, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria.
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View Article and Find Full Text PDFKhirurgiia (Mosk)
August 2024
Evdokimov Moscow State University of Medicine and Dentistry, Moscow, Russia.
Despite available armored personal protection in troops, the incidence of abdominal wounds in modern wars is 6.6-9.0%.
View Article and Find Full Text PDFTraditional surgical treatment of widespread purulent peritonitis has some disadvantages that emphasizes the need for new approaches to postoperative care. The authors present successful treatment of diffuse purulent peritonitis using a combination of 'open abdomen' technology and VAC therapy. This approach reduces abdominal inflammation and intra-abdominal pressure.
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