AI Article Synopsis
- - The case shows that cell-free parasite DNA can be a helpful diagnostic tool for identifying active schistosomiasis infections.
- - Unlike the quick drop in the presence of ova in urine after treatment, the parasite DNA was still detectable in various specimen types even after multiple treatments.
- - This finding aligns with the detection of intact ova in bladder biopsy samples and the symptoms experienced by the patient.
Article Abstract
This case of imported refractory schistosomiasis has highlighted the usefulness of cell-free parasite DNA as a diagnostic marker to assess active schistosome infection. In contrast to the rapid disappearance of ova in urine, parasite DNA remained persistent in several other specimen types even after the fourth treatment with praziquantel. This result was consistent with the presence of morphologically intact ova in bladder biopsy samples and with the corresponding symptoms.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811636 | PMC |
| http://dx.doi.org/10.1128/JCM.01219-13 | DOI Listing |
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