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In vitro evaluation of bioabsorbable poly(lactic acid) (PLA) and poly-4-hydroxybutyrate (P4HB) warp-knitted spacer fabric scaffolds for osteogenic differentiation.
Biomed Mater
January 2025
Biomechanics Research Centre (BMEC), School of Engineering, University of Galway, University Road, Galway, H91 TK33, IRELAND.
Bioabsorbable textile scaffolds are promising for bone tissue engineering applications. Their tuneable, porous, fibre based architecture resembles that of native extracellular matrix, and they can sustain tissue growth while being gradually absorbed in the body. In this work, immortalized mouse calvaria preosteoblast MC3T3-E1 cells were cultured in vitro on two warp-knitted bioabsorbable spacer fabric scaffolds made of poly(lactic acid) (PLA) and poly-4-hydroxybutyrate (P4HB), to investigate their osteogenic properties.
View Article and Find Full Text PDFLong-Term Follow-Up of Magmaris Bioabsorbable Scaffold: Unabsorbed and Protruding Tantalum Markers.
JACC Cardiovasc Interv
November 2024
Department of Cardiology, Lin-Kou Chang Gung Memorial Hospital, Taoyuan City, Taiwan.
Ventral Hernia Repair With a Hybrid Absorbable-permanent Preperitoneal Mesh.
Surg Laparosc Endosc Percutan Tech
December 2024
Department of Surgery, North Shore University Health System, Evanston, IL.
Article Synopsis
- - The study focused on evaluating the safety and effectiveness of the GORE SYNECOR Preperitoneal Biomaterial (PRE device) for ventral hernia repairs, involving a retrospective review of outcomes for 148 patients over more than a year post-surgery.
- - Results showed a low incidence of adverse events within 30 days (8.8% overall), with the main complications being surgical site infections (4.8%) and the need for reoperations (2.0%). Importantly, no hernia recurrences were reported during the study.
- - The findings suggest that the PRE device is both safe and effective for complex repairs, combining the benefits of absorbable and permanent mesh materials when placed in the retromuscular
A Spironolactone-Based Prototype of an Innovative Biomedical Patch for Wound Dressing Applications.
Int J Mol Sci
September 2024
Department of Pharmacy, University of Naples "Federico II" Via Domenico Montesano, 49, 80131 Napoli, NA, Italy.
The electrospinning process is an effective technique for creating micro- and nanofibers from synthetic and natural polymers, with significant potential for biomedical applications and drug delivery systems due to their high drug-loading capacity, large surface area, and tunable release times. Poly(L-lactic acid) (PLLA) stands out for its excellent thermo-mechanical properties, biodegradability, and bioabsorbability. Electrospun PLLA nanofibrous structures have been extensively investigated as wound dressings, sutures, drug delivery carriers, and tissue engineering scaffolds.
View Article and Find Full Text PDFWavelet-based U-shape network for bioabsorbable vascular stents segmentation in IVOCT images.
Front Physiol
August 2024
Henan Key Laboratory of Cardiac Remodeling and Transplantation, Zhengzhou Seventh People's Hospital, Zhengzhou, China.
Background And Objective: Coronary artery disease remains a leading cause of mortality among individuals with cardiovascular conditions. The therapeutic use of bioresorbable vascular scaffolds (BVSs) through stent implantation is common, yet the effectiveness of current BVS segmentation techniques from Intravascular Optical Coherence Tomography (IVOCT) images is inadequate.
Methods: This paper introduces an enhanced segmentation approach using a novel Wavelet-based U-shape network to address these challenges.
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