The optimal use of cardiac imaging in the quantification of carcinoid heart disease.

Endocr Relat Cancer

Department of Cardiology, Clinical Sciences Centre, University Hospital Aintree, Liverpool, UK.

Published: October 2013

Carcinoid heart disease is a rare cause of right-sided valvular dysfunction, primarily mediated by serotonin. It is an important complication in patients with carcinoid syndrome and occurs in 20-50% of such patients. Echocardiography is the main technique used for the assessment of carcinoid heart disease, but other imaging modalities are also important, particularly in the quantification of the severity of the disease. We sought to review the role of cardiac imaging in the assessment of carcinoid heart disease.

Download full-text PDF

Source
http://dx.doi.org/10.1530/ERC-13-0152DOI Listing

Publication Analysis

Top Keywords

carcinoid heart
16
heart disease
16
cardiac imaging
8
assessment carcinoid
8
carcinoid
5
disease
5
optimal cardiac
4
imaging quantification
4
quantification carcinoid
4
heart
4

Similar Publications

[An unusual tricuspid regurgitation].

G Ital Cardiol (Rome)

January 2025

U.O. Cardiologia, Dipartimento di Specialità Medico-Chirurgiche, Scienze Radiologiche e Sanità Pubblica, Università degli Studi, Brescia.

Tricuspid regurgitation can be due to different causes and mechanisms. Among these, cardiac involvement in carcinoid disease is a rare cause of tricuspid valve disease with a peculiar echocardiographic aspect. We report the case of a 59-year-old woman, with no past medical history, who was recently found to have a heart murmur and signs of right heart failure.

View Article and Find Full Text PDF

Background: Pulmonary carcinoids are rare neuroendocrine tumors accounting for less than 1% of all lung cancers. They are classified into two subcategories; typical and atypical carcinoids with the latter tending to grow faster. Historically, open thoracotomy was the standard approach for pulmonary resection.

View Article and Find Full Text PDF

Small intestinal neuroendocrine tumors (SI-NETs) are characterized by carcinoid syndrome and carcinoid heart disease (CHD). The aim of the present study was to identify early risk markers for carcinoid heart disease and survival in a prospective median-term follow-up setting. We measured 5-HIAA and cumulative 5-HIAA exposure (Cum-5-HIAA) based on repeated measurements, proBNP, vascular function, hepatic tumor load, and transthoracic echocardiography (TTE) at baseline and during the median 5-year follow-up.

View Article and Find Full Text PDF

Background: Following the publication of international cardio-oncology (CO) imaging guidelines, standard echocardiographic monitoring parameters of left ventricular systolic function have been endorsed. Recommendations highlight that either two-dimensional (2D) or three-dimensional (3D) left ventricular ejection fraction (LVEF), alongside global longitudinal strain (GLS) should be routinely performed for surveillance of patients at risk of cancer therapy-related cardiac dysfunction (CTRCD). We studied the feasibility of 3D-LVEF, 2D-GLS and 2D-LVEF in a dedicated CO service.

View Article and Find Full Text PDF
Article Synopsis
  • - Primary ovarian carcinoid tumors are extremely rare, accounting for less than 0.1% of ovarian cancers, and often present with symptoms like abdominal pain and bloating.
  • - A 54-year-old woman experienced dyspnea and edema, which were initially misdiagnosed as heart failure without classic carcinoid syndrome symptoms, but further tests indicated carcinoid disease.
  • - Surgical treatment included valve repair and removal of reproductive organs, underscoring the importance of prompt diagnosis and intervention for managing complications like carcinoid heart disease.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!