Background: obesity is a well-known risk factor for endometrial cancer, and both diseases are rising in Mexico. However, in our country some data indicates low influence of obesity on this neoplasm, and this is contradictory. Therefore, we explore the prevalence of obesity on women affected with this malignant tumor.
Methods: this was a pilot case-control study in a general hospital at Mexico City. The analysis involved obesity (a body mass index ≥ 30 kg/m(2)) diabetes mellitus and systemic arterial hypertension.
Results: the sample was of 66 women: 22 cases and 44 controls. In cases, obesity occurred in 77 % (odds ratio [OR] 8.1, 95 % confidence interval [CI] 2.46-26.6); diabetes mellitus in 41 % (OR 4.3, CI 1.31-14.7); and systemic arterial hypertension in 41 % (OR 2.3, CI 0.78-7.1).
Conclusions: these preliminary results suggested that obesity was the most frequent risk factor for these women with endometrial cancer.
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Environ Sci Technol
January 2025
Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98195, United States.
Enteropathogens are major contributors to mortality and morbidity, particularly in settings with limited access to water, sanitation, and hygiene infrastructure. To assess transmission pathways associated with enteropathogen infection, we measured household environmental conditions and assayed 22 enteropathogens using TaqMan Array Cards in stool samples from 276 six-month-old children living in communities along a rural-urban gradient in Northern Ecuador. We utilized multivariable models, risk factor importance, and distance-based statistical methods to test factors associated with infection.
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January 2025
EADV Task Force on Tattoos and Body Art, Lugano, Switzerland.
Heliyon
January 2025
Cancer Early Detection Advanced Research Center (CEDAR), Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA.
Neurosignaling is increasingly recognized as a critical factor in cancer progression, where neuronal innervation of primary tumors contributes to the disease's advancement. This study focuses on segmenting individual axons within the prostate tumor microenvironment, which have been challenging to detect and analyze due to their irregular morphologies. We present a novel deep learning-based approach for the automated segmentation of axons, AxonFinder, leveraging a U-Net model with a ResNet-101 encoder, based on a multiplexed imaging approach.
View Article and Find Full Text PDFCureus
December 2024
Department of Family Medicine, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, SAU.
Objectives This study analyzed the practices and findings on postpartum type 2 diabetes mellitus (T2DM) screening among pregnant women with gestational diabetes mellitus (GDM). Methods A retrospective cohort study was conducted at a tertiary care center in Western Saudi Arabia, between January 1, 2016, and December 31, 2018. It involved 642 nondiabetic women with a confirmed diagnosis of GDM, who were followed until delivery.
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