AI Article Synopsis

  • Goodpasture's syndrome during pregnancy is very rare, and the occurrence of anti-GBM disease requiring dialysis with subsequent renal recovery is even less common.
  • A 23-year-old woman in her first pregnancy developed Goodpasture's syndrome at 13 weeks and underwent aggressive treatment, including steroids, cytotoxic drugs, plasma exchange, and alternate day hemodialysis.
  • The patient's condition improved significantly, leading to normalized kidney function and a negative Anti-GBM antibody titer after the pregnancy was terminated at 15 weeks.

Article Abstract

Goodpasture's syndrome complicating pregnancy is extremely rare and dialysis requiring anti GBM disease with renal recovery is uncommon. We report a case of a 23-year-old primi gravida who presented with Goodpasture's syndrome during thirteenth week of pregnancy. She was initiated on steroids and cytotoxic drugs along with intensive plasma exchange and alternate day hemodialysis. Her pregnancy was terminated at 15 weeks. Patient improved dramatically with treatment, her renal functions normalized and her Anti GBM antibody titer became negative.

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Source
http://dx.doi.org/10.3109/0886022X.2013.815566DOI Listing

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