The vagotomy alleviates the anorectic effect of an excess amount of dietary leucine on rats fed a low-protein diet.

Biosci Biotechnol Biochem

Laboratory of Molecular Nutrition, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto 606-8522, Japan.

Published: February 2014

It is well known that large dose of leucine reduces the food intake and causes growth retardation in experimental animals when leucine is given with a low-protein diet. However, the mechanism for the anorectic effect of leucine has not yet been clarified. We demonstrate here that the anorectic effect of leucine was significantly reduced in a vagotomized rat.

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Source
http://dx.doi.org/10.1271/bbb.130150DOI Listing

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