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Current perspectives on topical antiallergics.
Indian J Ophthalmol
December 2024
Department of Cornea, Gokhale Eye Hospital, Mumbai, Maharashtra, India.
Allergy is one of the most common diagnoses in an ocular surface clinic, and its treatment can range from a simple lubricant to the most complex combinations of medications belonging to several diverse classes. Antiallergics are the most commonly used medication overall in all forms of allergy. Several options are available, and it is important to understand how to start, select, and continue their use.
View Article and Find Full Text PDFSmall fiber pathology in fibromyalgia syndrome.
Pain Rep
February 2025
Department of Neurology, University Hospital Würzburg, Würzburg, Germany.
About 50% of women with fibromyalgia syndrome have reduced skin innervation. This finding is consistent in patient cohorts from different regions of the world. Small fiber function may also be affected, as shown by various studies using different methods, such as quantitative sensory testing or special small fiber neurophysiology such as C-fiber microneurography.
View Article and Find Full Text PDFBlepharoptosis Associated With the Wearing of Hard Contact Lenses in Keratoconic Eyes.
Cureus
November 2024
Ophthalmology, International University of Health and Welfare, Chiba, JPN.
Keratoconus is a condition that causes progressive thinning and anterior protrusion of the cornea. Because of its irregular astigmatism, mild to moderate keratoconus is corrected with hard contact lenses (HCLs), but blepharoptosis due to the long-term wearing of HCLs is often a problem. In this study, we investigated blepharoptosis in HCL wearers with keratoconus.
View Article and Find Full Text PDFEvaluation of topical 1% posaconazole therapy in refractory fungal keratitis.
Indian J Ophthalmol
January 2025
Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.
Purpose: The primary objective was to evaluate the clinical response of refractory cases of fungal keratitis to topical 1% posaconazole therapy.
Methods: Prospective longitudinal non-randomized open label dual-cohort study of 70 eyes of refractory fungal keratitis, 35 were recruited as posaconazole treatment (PCZ) group for topical 1% posaconazole therapy and compared to 35 eyes on conventional antifungal therapy. Study parameters included demographic and treatment details, visual acuity, comprehensive slit-lamp biomicroscopy, clinical photography, ASOCT at recruitment and weekly (week 1, 2, 3 and 4 after treatment initiation).
Infectious keratitis in Western New York: a 10-year review of patient demographics, clinical management, and treatment failure.
Front Ophthalmol (Lausanne)
December 2024
Department of Ophthalmology, University of Rochester School of Medicine and Dentistry, Rochester, NY, United States.
Background: Infectious keratitis (IK) is a blinding disease and an important cause of ocular morbidity. Understanding regional trends in IK are important to understand the epidemiology and clinical outcomes of this disease.
Methods: In this 10-year retrospective review, patient characteristics including sociodemographic factors, medical history, and ocular history were collected as well as the clinical course and outcomes.
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