A short-cut review was carried out to establish whether measurement of the plasma calprotectin (S100A8/A9) level can be used to enable safe exclusion of acute appendicitis in children presenting to the emergency department with abdominal pain. Four studies were directly relevant to the question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are shown in table 3. The clinical bottom line is that there is currently no evidence to suggest that serum calprotectin is superior to standard inflammatory markers for the exclusion or confirmation of suspected appendicitis. Clinical examination findings remain the cornerstone of surgical decision-making.
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http://dx.doi.org/10.1136/emermed-2013-202918.3 | DOI Listing |
Implement Sci Commun
January 2025
Center for Dissemination and Implementation Science, Northwestern University Feinberg School of Medicine, 633 N St Clair Street, Chicago, IL, USA.
Background: Screening, Brief Intervention, and Referral to Treatment (SBIRT) is an evidence-based practice that can identify adolescents who use alcohol and other drugs and support proper referral to treatment. Despite an American College of Surgeons mandate to deliver SBIRT in pediatric trauma care, trauma centers throughout the United States have faced numerous patient, provider, and organizational level barriers to SBIRT implementation. The Implementing Alcohol Misuse Screening, Brief Intervention, and Referral to Treatment Study (IAMSBIRT) aimed to implement SBIRT across 10 pediatric trauma centers using the Science-to-Service Laboratory (SSL), an empirically supported implementation strategy.
View Article and Find Full Text PDFHealth Res Policy Syst
January 2025
Health Policy Research Group, Department of Pharmacology and Therapeutics, College of Medicine, University of Nigeria Enugu Campus, Enugu, Nigeria.
Background: There are massive gaps in communication between health researchers and policy-makers in Nigeria, which constrains the use of research evidence for policy-making. Mass media can help in bridging the gaps, especially since the media has the reach and a reputation for presenting information in ways that elicit actions from the public and policy-makers.
Objective: There is a small body of emerging literature from Nigeria and sub-Saharan Africa, evidencing the usefulness of the media to encourage evidence translation in the health sector; and even evidence translation theories are light on dissemination.
Fertil Steril
January 2025
Monash Centre for Health Research and Implementation, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia; Department of Diabetes and Vascular Medicine, Monash Health, Victoria, Australia. Electronic address:
Clinical practice guidelines (CPGs) are critical tools to inform healthcare decision-making, yet development faces significant challenges in ensuring rigorous, reliable, and globally applicable recommendations. This review examines the essential standards and evolving approaches for creating high-quality, evidence-based guidelines that can effectively support clinical practice across diverse healthcare settings. Key standards for high-quality CPG development emerge from leading global health organizations, emphasizing several critical components - establishing a multidisciplinary development group, defining a clear and relevant scope, conducting systematic evidence reviews and meta-analyses, and ensuring transparency throughout the development process.
View Article and Find Full Text PDFComput Biol Med
January 2025
Dept. Electrical Engineering and Computer Science, University of Stavanger, Kristine Bonnevies vei 22, Stavanger, 4021, Rogaland, Norway.
Around 5%-10% of newborns need assistance to start breathing. Currently, there is a lack of evidence-based research, objective data collection, and opportunities for learning from real newborn resuscitation emergency events. Generating and evaluating automated newborn resuscitation algorithm activity timelines relative to the Time of Birth (ToB) offers a promising opportunity to enhance newborn care practices.
View Article and Find Full Text PDFJ Perinat Neonatal Nurs
January 2025
Author Affiliations: Department of Children Health and Disease Nursing, Nursing Faculty, Selçuk University, Konya, Türkiye (Drs Taş Arslan and Küçükoğlu); Department of Medical Services and Techniques, First and Emergency Aid Program, Vocational School of Health Services, Kırsehir Ahi Evran University, Kırsehir, Türkiye (Ms Tar Bolacalı); Department of Medical Services and Techniques, Dialysis Program, Vocational High School, Lokman Hekim University, Ankara, Türkiye (Ms Tanrıkulu); and Neonatal Intensive Care Unit, Konya City Hospital, Konya, Turkey (Ms Ertürk).
Objective: This study aims to determine the internal and external factors affecting the attitudes of neonatal intensive care nurses toward evidence-based practices (EBP).
Methods: The population of this descriptive, cross-sectional, and relation-seeking multicenter study consisted of nurses working in 5 neonatal intensive care units located in 3 provinces of Türkiye. Data were collected using the Information Form, which included nurses' sociodemographic information and internal-external factors affecting evidence-based care practices, the Evidence-Based Nursing Attitude Questionnaire (EBNAQ).
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