In this paper, we propose a new supervised manifold learning approach, supervised preserving projection (SPP), for the depth images of a 3D imaging sensor based on the time-of-flight (TOF) principle. We present a novel manifold sense to learn scene information produced by the TOF camera along with depth images. First, we use a local surface patch to approximate the underlying manifold structures represented by the scene information. The fundamental idea is that, because TOF data have nonstatic noise and distance ambiguity problems, the surface patches can more efficiently approximate the local neighborhood structures of the underlying manifold than TOF data points, and they are robust to the nonstatic noise of TOF data. Second, we propose SPP to preserve the pairwise similarity between the local neighboring patches in TOF depth images. Moreover, SPP accomplishes the low-dimensional embedding by adding the scene region class label information accompanying the training samples and obtains the predictive mapping by incorporating the local geometrical properties of the dataset. The proposed approach has advantages of both classical linear and nonlinear manifold learning, and real-time estimation results of the test samples are obtained by the low-dimensional embedding and the predictive mapping. Experiments show that our approach obtains information effectively from three scenes and is robust to the nonstatic noise of 3D imaging sensor data.
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Nat Commun
January 2025
Interdisciplinary Science Center, State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, 100101, Beijing, China.
Fluorogenic RNA aptamers have various applications, including use as fluorescent tags for imaging RNA trafficking and as indicators of RNA-based sensors that exhibit fluorescence upon binding small-molecule fluorophores in living cells. Current fluorogenic RNA:fluorophore complexes typically emit visible fluorescence. However, it is challenging to develop fluorogenic RNA with near-infrared (NIR) fluorescence for in vivo imaging and sensing studies.
View Article and Find Full Text PDFAnal Chim Acta
January 2025
Key Laboratory of Luminescence Analysis and Molecular Sensing (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China. Electronic address:
Background: As global food production continues to surge, the widespread use of herbicides has also increased concurrently, posing challenges like health risks and environmental pollution. Traditional detection methods for pesticide residues, such as diquat (DQ), were hampered by limitations like high expenses, lengthy detection times and complex operations, restricting their practical application in rapid clinical diagnosis.
Results: In light of the pressing necessity for the identification of minute pesticide residues and the intrinsic constraints of small molecule analysis, a novel chromophotometric biosensor targeting small molecules was developed based on bi-epitopes on single antibody to immobilize two DQ-PAL, inhibiting the hybridization of DQ-PAL.
Anal Chim Acta
January 2025
The Education Ministry Key Laboratory of Resource Chemistry, Joint International Research Laboratory of Resource Chemistry, Ministry of Education, Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, Shanghai Frontiers Science Center of Biomimetic Catalysis and College of chemistry and materials science, School of Environmental and Geographical Sciences. Shanghai Normal University, Shanghai, 200234, People's Republic of China. Electronic address:
Background: Polycyclic aromatic hydrocarbons (PAHs) are one of the most dangerous persistent organic pollutants in the environment. Due to the discharge of chemical plants and domestic water, the existence of PAHs in sea water and lake water is harmful to human health. A method for rapid detection and removal of PAHs in water needs to be developed.
View Article and Find Full Text PDFAgeing Res Rev
January 2025
Department of Pharmaceutics, NIMS Institute of Pharmacy, NIMS University, Jaipur 303121, Rajasthan, India.
Neurodegenerative diseases (NDs) are debilitating disorders characterized by the progressive and selective loss of function or structure in the brain and spinal cord. Both chronic and acute forms of these diseases are associated with significant morbidity and mortality, as they involve the degeneration of neurons in various brain regions. Misfolding and aggregation of amyloid proteins into oligomer and β-sheet rich fibrils share as common hallmark and lead to neurotoxicity.
View Article and Find Full Text PDFProg Biomed Eng (Bristol)
January 2025
Amrita Vishwa Vidyapeetham, Center for Wireless Networks & Applications (WNA), Amrita Vishwa Vidyapeetham Amritapuri, Kollam, India, Kollam, 690525, INDIA.
Lymphedema is localized swelling due to lymphatic system dysfunction, often affecting arms and legs due to fluid accumulation. It occurs in 20% to 94% of patients within 2 to 5 years after breast cancer treatment, with around 20% of women developing breast cancer-related lymphedema (BCRL). This condition involves the accumulation of protein-rich fluid in interstitial spaces, leading to symptoms like swelling, pain, and reduced mobility that significantly impact quality of life.
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