Merging organocatalysis with transition metal catalysis and using O2 as the oxidant for enantioselective C-H functionalization of aldehydes.

A new catalytic Saegusa oxidation-Michael addition cascade reaction has been developed for the enantioselective β-functionalization of aldehydes. The feature of this research is the combination of organocatalysis and transition-metal catalysis for the asymmetric C-H functionalization which remains an underdeveloped research topic.