Purpose: To compare immediate and conventional loading of fixed full-arch maxillary prostheses supported by implants placed in healed and fresh postextraction sites.

Materials And Methods: This prospective, controlled, nonrandomized 12-month study included 30 consecutive patients requiring fixed full-arch maxillary prostheses supported by implants placed in healed and fresh extraction sites. Fifteen patients were treated with conventional loading (control group), and 15 were treated with immediate loading (test group). Each patient received six to eight implants; implants with insertion torque < 35 Ncm were conventionally loaded and excluded from the analysis. Implant success, biologic and prosthetic complications, success of the immediately loaded provisional prostheses, and marginal bone loss were assessed and analyzed statistically.

Results: One test group patient failed to attend recall visits and was excluded from the study, and 16 implants did not achieve insertion torque of 35 Ncm and were excluded from analyses. The final sample included 29 patients and 193 implants (94 test implants, 99 control implants). Implant success rates were 96.8% (test) and 99.0% (control). In the test group, the most common complications were screw loosening and tooth fractures; in the control group, dentures caused discomfort and soft tissue irritation. The success rate of the immediately loaded prostheses was 100%. Average bone loss was 0.61 ± 0.21 mm for test implants and 0.53 ± 0.18 mm for control implants. Differences between loading protocols were not statistically significant.

Conclusions: No significant differences in implant success and peri-implant marginal bone loss were seen in the current 12-month comparison of immediate and conventional loading of maxillary fixed full-arch prostheses. Biologic and prosthetic complications were rare with both loading protocols, and all immediately loaded provisional fixed prostheses performed successfully.

Download full-text PDF

Source
http://dx.doi.org/10.11607/jomi.3119DOI Listing

Publication Analysis

Top Keywords

conventional loading
16
fixed full-arch
12
test group
12
implant success
12
bone loss
12
implants
11
extraction sites
8
full-arch maxillary
8
maxillary prostheses
8
prostheses supported
8

Similar Publications

Charge Regulation-Enhanced Type I Photosensitizer-Loaded Hydrogel Dressing for Hypoxic Bacterial Inhibition and Biofilm Elimination.

ACS Nano

January 2025

State Key Laboratory of Fine Chemicals, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518055, China.

Biofilm-induced chronic bacterial infections represent a significant challenge in modern medicine due to their resistance to conventional antibiotic treatments. Although photodynamic therapy (PDT) has emerged as a promising antibiotic-free antibacterial strategy, the hypoxic condition within biofilms and the lack of an effective local drug delivery system have limited the clinical effectiveness of photosensitizer (PS) agents. Herein, we propose a type of charge regulation-enhanced type I PS-loaded hydrogel dressing for treating biofilm infection.

View Article and Find Full Text PDF

Carrier-Free, Hyaluronic Acid-Modified Self-Assembled Doxorubicin, and Chlorin e6 Nanoparticles Enhance Combined Chemo- and Photodynamic Therapy in vivo.

Int J Nanomedicine

January 2025

State Key Laboratory of Ophthalmology, Optometry and Visual Science, National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.

Background: Developing carrier-free nanomedicines via self-assembly of two antitumor drug molecules is a potential strategy for enhancing the combination treatment of tumors. Similarly, conventional chemotherapy combined with photodynamic therapy may synergistically improve the antitumor effect while minimizing the adverse reactions associated with antitumor treatment. Hyaluronic acid (HA) can bind to overexpressed HA receptors on the tumor cell surface, increasing cell internalization and resulting in good tumor-targeting properties.

View Article and Find Full Text PDF

Since its introduction, vaccination has heavily improved health outcomes. However, implementing vaccination efforts can be challenging, particularly in low and middle-income countries with warmer climates. Microneedle technology has been developed for its simple and relatively painless applications of vaccines.

View Article and Find Full Text PDF

Whey Protein-Based Hydrogel Microspheres for Endovascular Embolization.

ACS Appl Bio Mater

January 2025

Department of Radiology, University of Minnesota, Minneapolis, Minnesota 55455, United States.

Transarterial embolization (TAE) is an image-guided, minimally invasive procedure for treating various clinical conditions by delivering embolic agents to occlude diseased arteries. Conventional embolic agents focus on vessel occlusion but can cause unintended long-term inflammation and ischemia in healthy tissues. Next-generation embolic agents must exhibit biocompatibility, biodegradability, and effective drug delivery, yet some degradable microspheres degrade too quickly, leading to the potential migration of fragments into distal blood vessels causing off-target embolization.

View Article and Find Full Text PDF

Colloid-Forming Prodrug-Hydrogel Composite Prolongs Lower Intraocular Pressure in Rodent Eyes after Subconjunctival Injection.

Adv Mater

January 2025

Department of Chemical Engineering & Applied Chemistry, University of Toronto, 200 College Street, Toronto, ON, M5S 3E5, Canada.

Colloidal drug aggregates (CDAs) are challenging in drug discovery due to their unpredictable formation and interference with screening assays. These limitations are turned into a strategic advantage by leveraging CDAs as a drug delivery platform. This study explores the deliberate formation and stabilization of CDAs for local ocular drug delivery, using a modified smallmolecule glaucoma drug.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!