Four new diterpenes from Aphanamixis polystachya.

Fitoterapia

Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, PR China.

Published: October 2013

Four novel diterpenes possessing rare five-membered peroxide ring, aphanaperoxides E-H (1-4), were isolated from stem bark of Aphanamixis polystachya. Their structures including the absolute configuration were elucidated by spectroscopic data and CD analysis. The cytotoxicities of the isolated compounds against a panel of human cancer cell lines were evaluated.

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Source
http://dx.doi.org/10.1016/j.fitote.2013.07.008DOI Listing

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