AI Article Synopsis
- The study aimed to investigate how common benign gynecological disorders relate to epithelial ovarian cancer (EOC) by reviewing medical records of 226 patients.
- It was found that endometriosis significantly co-existed with the clear cell and endometrioid types of EOC but not with high grade serous cancer.
- In contrast, other benign disorders like uterine myoma, adenomyosis, and endometrial polyps showed no significant association with different EOC subtypes.
Article Abstract
Objective: To explore the association between epithelial ovarian cancer (EOC) and common benign gynecological disorders.
Study Design: The medical records of 226 patients with EOC treated at Peking Union Medical College Hospital between March 2011 and March 2012 were reviewed. Histological evaluations had been performed to determine the presence of coexisting pelvic endometriosis (n=17), uterine leiomyoma (n=66), adenomyosis (n=22), or endometrial polyps (n=17).
Results: Coexistence of endometriosis occurred in 35.3% and 36.4% of cases of the clear cell and endometrioid subtypes of EOC histology, respectively. Endometriosis was more likely associated with clear cell or endometrioid ovarian carcinoma, but less likely with high grade serous cancer. No differences were observed in the concurrence of uterine myoma, adenomyosis or endometrial polyps among the different subtypes of EOC.
Conclusions: In contrast to other common benign gynecological disorders, endometriosis showed close relationships with the clear cell and endometrioid subtypes of EOC specifically.
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| http://dx.doi.org/10.1016/j.ejogrb.2013.06.015 | DOI Listing |
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