Background: Lipomas are common benign mesenchymal tumors commonly removed using excision, but in certain cases, surgery is undesirable or ineffective. High-intensity focused ultrasound (HIFU) offers a noninvasive tumor ablation tool increasingly used in the clinic.
Objective: To evaluate the efficacy and safety of a noninvasive lipoma size reduction technology using HIFU.
Materials & Methods: Twelve lipomas in nine patients were treated. Patients underwent four treatment sessions with a 3-week interval between treatments. Blood and urine tests and tolerability based on a standard visual analogue scale (VAS) were used to monitor patients for adverse effects. Lipoma volume was determined by measuring width and length (manually) and depth (ultrasonically).
Results: The range of lipoma size was 2.7-169.4 cm3 before treatment and 0.2-119.8 cm3 after treatment. Mean volume reduction was 58.1 ± 22.8%. When palpated, the lipomas felt much softer than before treatment. The average VAS score was 4.1 ± 2.4. No significant adverse effects were noted.
Conclusion: The treatment was shown to be effective in noninvasively reducing lipoma size. The average volume reduction was substantial and statistically significant. The treatment was safe and well-tolerated. HIFU may be an alternative treatment modality in cases of lipoma.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/dsu.12269 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Vitamin D Therapy May Induce Lipoma Involution: A Multi-case Report.
Cureus
November 2024
Plastic Surgery, The University of Chicago Medicine, Chicago, USA.
Benign lipomas are a common medical problem that is not known to regress spontaneously. In addition, vitamin D (VD) is a known regulator of adipocyte proliferation and differentiation. Thus, the purpose of this multi-case study was to determine if optimizing serum 1,25(OH)D3 (VD3) concentrations to the 40-60 ng/mL range would catalyze regression of benign subcutaneous lipomas.
View Article and Find Full Text PDFConstricting colonic lipoma causing acute intestinal obstruction.
J Surg Case Rep
January 2025
Faculty of Medicine, Kilimanjaro Christian Medical University College, PO Box 2240, Moshi, Tanzania.
Colon lipomas are rare benign, nonepithelial tumors that are often asymptomatic. However, when symptoms do occur, they vary depending on the size and location of the lipoma and are generally nonspecific. Diagnosis is confirmed through histopathological analysis.
View Article and Find Full Text PDFA massive cardiac lipoma in the right atrium with multimodality imaging.
J Cardiothorac Surg
December 2024
Department of Ultrasound, Yanan Hospital of Kunming City, Kunming, Yunnan Province, China.
We report the noninvasive imaging diagnosis of a massive right atrial lipoma in a young male patient. Echocardiography and myocardial contrast echocardiography were used to assess echo intensity, tumor size, anatomic boundary, hemodynamics, and contrast agent perfusion. Dual-source CT revealed that the CT value of the tumor was fat density.
View Article and Find Full Text PDFLaparoscopic approach in the surgical treatment of large retrorectal tumors: a short-term experience at a single tertiary center case series in Korea.
J Minim Invasive Surg
December 2024
Department of Surgery, Chonnam National University Hospital, Gwangju, Korea.
Retrorectal tumors, although rare, pose diagnostic and treatment challenges due to their nonspecific symptoms and complex anatomical location. This single-center case series reports short-term outcomes of laparoscopic transabdominal resection as a surgical approach for large retrorectal tumors. Between 2017 and 2020, five patients underwent this procedure.
View Article and Find Full Text PDFAdult Intussusception in Jordan: Demographics, Clinical Features, and Outcomes from a Tertiary Hospital.
Med Sci Monit Basic Res
December 2024
Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Article Synopsis
- Adult intussusception (AI) is a rare condition in patients over 18 that presents with various symptoms, often requiring surgical treatment, and is primarily diagnosed using CT scans.
- A study of 26 cases revealed that the condition is more common in males with an average age of 53, where the most frequent symptom is abdominal pain; however, bleeding per rectum is notably linked to more severe, malignant causes.
- Understanding the characteristics and predictive factors of AI can help in managing the condition effectively, emphasizing the importance of a multidisciplinary approach in treatment strategies.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!