Elliptical particle motion, often encountered in acoustic fields containing interference between a source signal and its reflections, can be quantified by the degree of circularity, a vector quantity formulated from acoustic particle velocity, or vector intensity measurements. Acoustic analysis based on the degree of circularity is expected to find application in ocean waveguides as its spatial dependence relates to the acquisition geometry, water column sound speed, surface conditions, and bottom properties. Vector sensor measurements from a laboratory experiment are presented to demonstrate the depth dependence of both the degree of circularity and an approximate formulation based on vertical intensity measurements. The approximation is applied to vertical intensity field measurements made in a 2006 experiment off the New Jersey coast (in waters 80 m deep) to demonstrate the effect of sediment structure on the range dependence of the degree of circularity. The mathematical formulation presented here establishes the framework to readily compute the degree of circularity from experimental measurements; the experimental examples are provided as evidence of the spatial and frequency dependence of this fundamental vector property.
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http://dx.doi.org/10.1121/1.4807747 | DOI Listing |
Curr Eye Res
December 2024
Ophthalmology Department, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Anal Chem
December 2024
Institute of Organic Chemistry and Biochemistry of the Academy of Sciences, Flemingovo Nám. 2, Prague 16610, Czech Republic.
Most currently marketed pharmaceuticals are manufactured in the solid state, where the bioavailability of the active pharmaceutical ingredient (API) can be optimized through different polymorphs, cocrystals, solvates, or salts. Efficient techniques are needed to monitor the structure of pharmaceuticals during production. Here, we explore the potential of linearly and circularly polarized Raman microscopy for distinguishing three polymorphs of sofosbuvir, an antiviral drug used to treat hepatitis C.
View Article and Find Full Text PDFMicrosc Microanal
November 2024
Radioisotope Science and Technology Division, Oak Ridge National Laboratory, Oak Ridge, TN 37830, USA.
The production of plutonium-238 through irradiation of neptunium-237 (237Np) target materials for the use in radioisotope thermoelectric generators is paramount for continued deep space exploration. This work employs scanning electron microscopy to analyze 237Np materials coupled with a well-developed image analysis framework (Morphological Analysis for Material Attribution, or MAMA) to determine the degree of micron-scale homogeneity in the materials. This work demonstrated how the quantification of particle characteristics can validate production materials and affirm the qualitative similarities observed in micrographs.
View Article and Find Full Text PDFCytometry A
December 2024
Laboratory of Translational Oncology, Intercollegiate Faculty of Biotechnology, Medical University of Gdańsk, Gdańsk, Poland.
BMC Ophthalmol
October 2024
Department of Ophthalmology, EYE & ENT Hospital of Fudan University, 19 Baoqing Road, Shanghai, 200031, China.
Aims: To investigate the fundus characteristics and macular optical coherence tomography angiography (OCTA) metrics in patients with myelinated retinal nerve fibers (MRNF) and to identify the associations among myopic parameters, fundus metrics, and OCTA metrics.
Methods: The single-center case-control study included 15 patients with monocular MRNF and 15 patients without MRNF, matched for age, affected eyes' spherical equivalent error (SER), and axial length (AL) between May 2021 and December 2021. Fundus features, including the entire MRNF area (Area1), the denser MRNF area (Area2), and the shortest distance from the fovea to the MRNF border (D), along with ocular parameters, including SER, AL, best corrected visual acuity (BCVA), and OCTA metrics at the fovea, including choroidal (ChT) and retinal (ReT) thicknesses at the fovea, the foveal avascular zone area (FAZ), foveal avascular zone perimeter (FAZP), FAZ-circularity index (FAZ-CI), and foveal vessel density in a 300-µm wide region (FD-300), were assessed.
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