Tafluprost is an FP receptor antagonist that has been shown in clinical studies in Europe and Japan to be extremely useful in treating elevated intraocular pressure and glaucoma. The drug is well tolerated and appears to be at least equal in effectiveness and perhaps superior to other protanoids for routine use comparison to be superior to other treatments for the elevated IOP as the side effects and other related symptomology appear to be less, while maintaining a level of pressure control for prolonged periods.
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| http://dx.doi.org/10.4137/OED.S4253 | DOI Listing |
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Evidence in Practice: A Review of Real-Life Studies and Clinical Experience with the Preservative-Free Tafluprost (0.0015%) and Timolol (0.5%) Fixed-Dose Combination.
Clin Ophthalmol
November 2024
Tutkimusz Ltd., Solymár, Hungary.
The preservative-free fixed-dose combination formulation of 0.0015% tafluprost and 0.5% timolol (PF tafluprost/timolol FC) is among the topical intraocular pressure (IOP)-lowering therapies commonly used second-line for the management of ocular hypertension (OHT) and open-angle glaucoma (OAG), according to recommended treatment pathways.
View Article and Find Full Text PDFEfficacy of preserved Tafluprost 0.0015% in lowering intraocular pressure.
Indian J Ophthalmol
December 2023
Glaucoma Service, B B Eye Foundation, "Sukhsagar", 2/5, Sarat Bose Road, Kolkata, West Bengal, India.
Objective: To investigate the intraocular pressure (IOP) lowering effect of topical preserved tafluprost 0.0015% in a tertiary hospital setting in India.
Methods: This is a retrospective chart review of patients with primary open-angle glaucoma (POAG) or ocular hypertension (OHT) attending regular outpatient visits in December 2019 and January 2021, and treated with topical preserved tafluprost 0.
The evaluation of the effect of tafluprost on the intraocular pressure of healthy male guinea pigs under different light-and-darkness regimes.
Vet Med Sci
May 2023
Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, The Science and Research Branch of Islamic Azad University, Tehran, Iran.
Background: Ocular hypertension is one of the most underdiagnosed ocular abnormalities among guinea pigs around the world.
Objectives: The current study investigates the effect of 0.0015% preservative-free tafluprost ophthalmic solution (Zioptan) on the intraocular pressure of 16 healthy male guinea pigs (Cavia porcellus) under different light/darkness regimes.
Effect of Topical Prostaglandin Analogue Therapy on Central Corneal Thickness: A Systematic Review.
J Clin Med
December 2022
Department of Preventive Medicine, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
To investigate whether prostaglandin analogue (PGA) eyedrops have a significant effect on central corneal thickness (CCT), we conducted a systematic search of literature published from 2000 to 2021. Among the studies conducted on topical PGA therapy in open-angle glaucoma or ocular hypertension patients over 18 years old, prospective studies with CCT change as an outcome were included. A single-arm meta-analysis was conducted to assess the overall effect on CCT, and subgroup analysis according to exposure time of PGA eyedrops was also performed.
View Article and Find Full Text PDF[Comparative evaluation of hypotensive effectiveness of topical monotherapy and selective laser trabeculectomy].
Vestn Oftalmol
October 2022
Research Institute of Eye Diseases, Moscow, Russia.
Purpose: Comparison of the hypotensive effects of selective laser trabeculoplasty (SLT) and drug therapy in patients with newly diagnosed primary open-angle glaucoma (POAG) and ocular hypertension.
Material And Methods: Thirty patients (30 eyes) with newly diagnosed ophthalmic hypertension or POAG were observed. Patients of the 1st group (15 eyes) underwent standard SLT as a starting treatment, patients of the 2nd group (15 eyes) were prescribed monotherapy with a prostaglandin analog.
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