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Diagnosis, treatment, and management of Mpox in urban Informal Settlements in Southwestern Nigeria: an ethnographic approach.
BMC Public Health
January 2025
Health & Nutrition Cluster, Institute of Development Studies, University of Sussex, Brighton, UK.
Background: Global re-emergence of the zoonotic viral disease, Mpox (Monkeypox) has drawn global attention, leading to its declaration as a Public Health Emergency of International Concern (PHEIC) by World Health Organisation (WHO) in July 2022. Nigeria is a spotlight identified for the viral disease outbreak, with attention drawn on its transmission to non-endemic nations. With the country's healthcare challenges, care seeking practices particularly amongst low-income urban informal settlement populations are diverse - presenting challenges to both case identification and management during an outbreak.
View Article and Find Full Text PDFCRISPR/Cas system and its application in the diagnosis of animal infectious diseases.
FASEB J
December 2024
State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agriculture Sciences, Lanzhou, China.
Infectious diseases are a serious threat to the existence of animals and humans' life. In the 21st century, the emergence and re-emergence of several zoonotic and non-zoonotic global pandemic diseases of socio-economic importance has affected billions of humans and animals. The need for expensive equipment and laboratories, non-availability of on-site testing abilities, with time-consuming and low sensitivity and specificity issues of currently available diagnostic techniques to identify these pathogenic micro-organisms on a large scale highlighted the need for developing cheap, portable environment friendly diagnostic methods.
View Article and Find Full Text PDFMonkeypox: A comprehensive review on mutation, transmission, pathophysiology, and therapeutics.
Int Immunopharmacol
December 2024
School of Chemical and Biomolecular Engineering, Pusan National University, Busan, South Korea. Electronic address:
Monkeypox virus (MPXV) is the causative agent of the monkeypox (Mpox) disease, belongs to the Orthopoxvirus genus of the Poxviridae family. Due to the recent re-emergence of Mpox in 2024, this is the second time when the World Health Organization (WHO) declared Mpox as a Public Health Emergency of International Concern (PHEIC). This review intends to offer an in-depth analysis of Mpox, including its key characteristics, epidemiological, mutation, pathophysiology, transmission, and therapeutics.
View Article and Find Full Text PDFEffectiveness of a scenario-based, community-based intervention in containing COVID-19 in China.
Front Public Health
December 2024
Weifang People's Hospital, Shandong Second Medical University, Weifang, China.
Article Synopsis
- The COVID-19 pandemic has notably affected health, social order, and economies, with potential new variants highlighting the need for effective community response strategies against severe respiratory diseases.
- An improved SEIR model was used to simulate and analyze the spread of various COVID-19 strains in a population of 2 million in Shandong Province, China, across multiple scenarios factoring in and comparing natural epidemic development versus the implementation of non-pharmaceutical interventions (NPIs).
- Results indicated that different NPIs yield varying effects on disease spread, emphasizing the importance of timely and appropriate community control measures and vaccinations in managing outbreaks.
Silent St. Louis encephalitis virus circulation evidence by a haemovigilance survey in a centralized blood bank.
J Public Health (Oxf)
November 2024
Fundación Banco Central de Sangre, 5000 Córdoba, Córdoba, Argentina.
Background: Saint Louis encephalitis virus (SLEV) re-emergence and its geographical expansion, evidenced by its emergence in previously unaffected areas, have raised significant public health concerns. We aimed to show the usefulness of haemovigilance as an effective tool to fill arboviruses surveillance gaps to track trends and identify hotspots.
Methods: Within the framework of a blood bank haemovigilance program, we performed a survey to evaluate the potential threat of circulating mosquito-borne infections for transfusion safety.
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