Objective: To present the initial clinical experience with robot-assisted partial adrenalectomy using indocyanine green dye with near-infrared fluorescence (ICG-NIRF) imaging.
Methods: Three consecutive patients with solitary adrenal masses with worrisome features were referred for treatment. The preoperative workup included dedicated axial imaging and adrenal function studies. All patients underwent purely robotic partial adrenalectomy with ICG-NIRF guidance. Relevant steps of the technique included a transperitoneal approach, gross identification of the adrenal gland, administration of 5 mg intravenous ICG, and finally, mass resection guided by ICG-NIRF and white light visualization in an effort to completely excise the mass while sparing uninvolved adrenal tissue.
Results: Robotic partial adrenalectomy was successfully performed with negative margins in all patients. All masses were hypofluorescent relative to normal adrenal tissue with ICG-NIRF and included a pheochromocytoma, lipoadenoma, and follicular lymphoid hyperplasia.
Conclusion: Robotic partial adrenalectomy with intraoperative ICG-NIRF is safe and feasible. The addition of ICG-NIRF may help mass identification, excision, and promote the use adrenal-sparing surgery.
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http://dx.doi.org/10.1016/j.urology.2013.03.074 | DOI Listing |
J Vasc Interv Radiol
December 2024
Department of Radiology, Tianjin Medical University General Hospital, Anshan Road 154#, Heping District, Tianjin, 300052, China. Electronic address:
Thirty-five patients diagnosed with aldosterone-producing adenomas underwent CT-guided percutaneous microwave ablation (MWA). Comparisons of aldosterone-to-renin ratio (ARR), potassium level, blood pressure (BP), and medications were performed preoperatively, postoperatively, and at the latest follow-up examination. The outcome assessment was based on the primary aldosteronism surgical outcome (PASO) Standards.
View Article and Find Full Text PDFEndocr Oncol
January 2024
Department of Molecular Imaging and Therapeutic Nuclear Medicine, Peter MacCallum Cancer Centre, Melbourne, Australia.
Background: Metastatic gastroenteropancreatic neuroendocrine neoplasms (GEPNEN) can cause ectopic Cushing's syndrome (ECS). ECS is highly morbid and medical therapy is complex and can be ineffective. Patients unsuitable for bilateral adrenalectomy (BA) have dismal outcomes.
View Article and Find Full Text PDFHormones (Athens)
November 2024
Centre for Endocrine Surgery, University College London Hospitals NHS Foundation Trust, 250 Euston Road, London, NW1 2PG, UK.
Case Rep Oncol
November 2024
Division of Hematology/Oncology/Blood and Marrow Transplantation, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
Introduction: Von Hippel-Lindau (VHL) is a diagnosis that leads to increased risk of tumor development over the course of a patient's lifetime. Patients with VHL undergo screening for multiple tumor types, including pheochromocytomas (PCCs). There is variability among the different international guidelines regarding the age to begin PCC screening, with most suggesting 5 years for screening initiation.
View Article and Find Full Text PDFWorld J Surg
November 2024
Department of Surgery and Center of Minimally Invasive Surgery, Evang. Kliniken Essen-Mitte, Academic Teaching Hospital of the University of Duisburg-Essen, Essen, Germany.
Background: Partial adrenalectomy (PA), as an alternative to total adrenalectomy in selected cases, allows for the preservation of adrenocortical function, especially in hereditary and/or bilateral diseases. In this study, we analyze our experience in posterior retroperitoneoscopic PA (PRPA) and its impact on adrenocortical function.
Patients And Methods: From January 2010 to December 2023, 709 PRPAs were performed on 766 adrenal glands in a total of 697 patients (421F; 276M; and mean age 49.
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