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All You Need to Know About Allometric Scaling: An Integrative Review on the Theoretical Basis, Empirical Evidence, and Application in Human Pharmacology.
Clin Pharmacokinet
December 2024
Division of Systems Pharmacology and Pharmacy, Leiden Academic Center for Drug Research, Leiden University, Leiden, The Netherlands.
Scaling approaches are used to describe or predict clearance for paediatric or obese populations from normal-weight adult values. Theoretical allometry assumes the existence of a universal bodyweight-based scaling relationship. Although theoretical allometry is highly disputed, it is commonly applied in pharmacological data analyses and clinical practice.
View Article and Find Full Text PDFHOW CAN SCHEMA THERAPY HELP US UNDERSTAND KIERKEGAARD'S BREAKING UP OF HIS ENGAGEMENT.
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PPclinic-København, Copenhagen, Denmark.
Søren Aabye Kierkegaard (1813-1855) is a great Danish philosopher and the father of existentialism. An essential part of his writings, often under pseudonyms, dealt with his broken engagement, reflecting his doubts and ambivalent feelings. The motives behind the breakup initiated by the philosopher are complex and hard to decipher.
View Article and Find Full Text PDFCountermeasures and follow-up actions in response to information on thyroid cancer, which possibly provoked misunderstanding and unfounded rumour, issued by five former Japanese prime ministers.
Radiat Prot Dosimetry
November 2024
Department of Radiation Health Management, Fukushima Medical University School of Medicine, Hikarigaoka-1 Fukushima City, Fukushima, Japan.
This study summarises the responses to information on thyroid cancer, which possibly provoked misunderstanding and unfounded rumour, described in a letter issued by five former Japanese Prime Ministers on 27 January, 2022. Fukushima Medical University (FMU) implemented countermeasures and follow-up in three phases in response to the letter. In Phase 1, FMU shared scientific facts on the relationship between radiation exposure and thyroid cancer, as well as the response of FMU towards those who read the letter and were concerned about the description.
View Article and Find Full Text PDFAs of October 1, 2024, Japan implemented a revised COVID-19 vaccination strategy, shifting from a fully publicly funded model to one where costs are partially or fully borne by recipients. This new annual program targets individuals aged 65 and above, and those aged 60-64 at higher risk of severe illness, requiring them to cover some vaccination expenses. For others, the vaccine remains voluntary and self-funded.
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