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Respiratory Physiological Reactions During Expiratory Muscle Training in Patients with Stable Severe Chronic Obstructive Pulmonary Disease (COPD).
Physiol Behav
December 2024
State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. Electronic address:
Object: This study aimed to investigate the physiological responses of patients with severe Chronic Obstructive Pulmonary Disease (COPD) during incremental expiratory resistive loading (ERL).
Method: Nine stable subjects with very severe COPD and hypercapnia were recruited. Baseline data were collected through spontaneous breathing for 10 minutes without resistive load.
Managing supraventricular tachyarrhythmia in pregnant patients within the emergency department.
Front Cardiovasc Med
December 2024
Department of Cardiology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.
Background: Pregnancy increases the risk of supraventricular tachycardia (SVT) due to physiological changes. This study reviews the management of SVT in pregnant patients in the emergency department (ED).
Methods: We retrospectively analyzed 15 pregnant patients with SVT treated at Shenzhen Second People's Hospital ED from 2015 to 2023.
VACStent closure of oesophageal defects by covered stent and endoscopic vacuum therapy: initial use and clinical outcomes.
J Surg Case Rep
January 2025
Department of Surgery, Mercy University Hospital, Grenville Place, Cork, T12 WE28, Ireland.
Endoscopic management of transmural oesophageal defects following esophagectomy or spontaneous perforations, such as Boerhaave's syndrome, is often complicated by stent migration and luminal occlusion [1]. The Vacuum-Assisted Closure (VAC) stent, which integrates a covered stent with endoscopic vacuum therapy, aims to address these issues by providing functional drainage and promoting wound healing [2]. This case series presents our initial experience with VACStent therapy in four patients treated between February 2023 and April 2024.
View Article and Find Full Text PDFUsing right colon interposition in patients with caustic ingestion, an introduction of a new surgical technique for post-gastrectomy reconstruction: a case series.
J Med Case Rep
December 2024
Shiraz Organ Transplant Center,, Abu Ali Sina Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: Corrosive substance ingestion is rare but can cause severe injury, especially to the upper gastrointestinal tract, and can be a potentially fatal event. Various surgical procedures have been advocated for gastroesophageal reconstruction, but especially those using the right colon, when the ileocecal valve is preserved for gastric reconstruction, are briefly exposed in literature and have not been studied in humans by controlled studies. Using the right colon is believed to be beneficial because of the anti-reflux mechanism of the ileocecal valve.
View Article and Find Full Text PDFNasal High Flow to Modulate Dyspnea in Orally Intubated Patients.
Am J Respir Crit Care Med
December 2024
APHP, Groupe Hospitalier Pitie Salpêtrière, Medecine intensive Reanimation, Paris, France.
Rationale: High flow therapy reduces dyspnea in acute respiratory failure but the underlying mechanisms are not fully elucidated.
Objectives: To compare dyspnea, airway occlusion pressure (P) and inspiratory work with and without nasal high flow (NHF, FiO 21%, temperature 31°C) in intubated patients under pressure support ventilation and during a spontaneous breathing trial (SBT).
Methods: Dyspnea (numerical rating scale, NRS and Mechanical Ventilation - Respiratory Distress Observational Scale, MV-RDOS), P, esophageal pressure, respiratory muscles EMG, arterial blood gas were compared in intubated patients on pressure support ventilation presenting a dyspnea-NRS > 3 during two sequences: 1) pressure support ventilation with NHF at 0 L/min followed by 30, 50 and 60 L/min (the last three were randomized) and 2) a SBT with NHF at 0 and 50 L/min (randomized).
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