Diltiazem-induced Transient Complete Atrioventricular Block in an Elderly Patient with Acute on Chronic Renal Failure.

Open Cardiovasc Med J

Department of Medicine, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.

Published: July 2013

Diltiazem is a calcium channel blocker commonly used in the treatment of various cardiovascular disorders such as hypertension, angina and supraventricular tachycardias. Metabolism occurs mainly in the liver, but a small percentage of unchanged drug and metabolites are excreted in the urine. Toxicity from this medication usually presents in the form of dysrrhytmias and heart block. Hence, we present a case of complete atrioventricular AV block in a patient receiving sustained- release diltiazem on a chronic basis. Risk factors such as advanced age and impaired renal function are dis-cussed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680986PMC
http://dx.doi.org/10.2174/1874192401307010023DOI Listing

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