Germline mutations in BRCA genes have been associated with pancreatic cancer. Laboratory and clinical data suggest that patients with BRCA mutations may be more responsive to therapy consisting of conventional chemotherapy with a poly(ADP-ribose) polymerase inhibitor (PARPi). The most recent data from the 2013 American Society of Clinical Oncology (ASCO) Annual Meeting will be reviewed (Abstracts #11024 and #TPS4144).
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.6092/1590-8577/1652 | DOI Listing |
Publication Analysis
Top Keywords
pancreatic cancer
8
brca pancreatic
4
cancer germline
4
germline mutations
4
mutations brca
4
brca genes
4
genes associated
4
associated pancreatic
4
cancer laboratory
4
laboratory clinical
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!