Objective: To evaluate the significance of umbilical cord chitotriosidase concentrations in pregnancies with mild preeclampsia and explore the relationship between fetal chitotriosidase levels and fetal blood flow velocity.

Method: The study population included control group (n=40) and study group with mild preeclampsia (n=40). Umbilical cord blood samples were collected immediately after delivery. Umbilical artery (UA) flow velocity waveform was determined just before delivery.

Results: Umbilical cord chitotriosidase levels and UA S/D rate were significantly high in preeclamptic group.

Conclusion: Chitotriosidase may be useful biochemical marker of fetal compromise that reflects the severity of fetoplacental blood flow resistance in pregnancies complicated by preeclampsia.

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http://dx.doi.org/10.3109/10641955.2013.810239DOI Listing

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