An enantioselective synthesis of the core framework of neurotrophic Illicium majucin-type sesquiterpenes is described here. This strategy is based on an organocatalyzed asymmetric Robinson annulation and provides an efficient approach for a diversity-oriented synthesis of Illicium natural products that holds remarkable therapeutic potential for neurodegenerative diseases.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701413 | PMC |
| http://dx.doi.org/10.3762/bjoc.9.126 | DOI Listing |
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