A Nd:YVO4 crystal consisting of three segments with different doping concentrations is originally developed for power scaling in diode-end-pumped solid-state laser. We systematically make a comparison of laser characteristics between the multi-segmented and conventional composite crystals to show the feasibility of using gain medium with multiple doping concentrations for power scale-up in end-pumped laser without introducing significant thermally accompanied effects. We further construct a dual-end-pumped actively Q-switched oscillator at 1064 nm to verify the usefulness of our crystal design, where the largest pulse energy of 1.06 mJ and the highest output power of 45 W are efficiently generated.
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http://dx.doi.org/10.1364/OE.21.016063 | DOI Listing |
AAPS J
January 2025
National Center On Addiction and Doping, National Institute of Health, Viale Regina Elena 299, 00161, Rome, Italy.
Nowadays, synthetic cathinones (SCs) is the second more representative subclass of New Psychoactive Substances, accounting for 104 analogues in the illegal market. Since its first report in 2011, α-pyrrolidinovalerophenone (α-PVP) gained popularity among drug users, provoking an increased number of intoxications. Nonetheless, pharmacokinetics data is still limited in the literature.
View Article and Find Full Text PDFAnal Chim Acta
January 2025
Shandong Provincial Key Laboratory of Chemical Energy Storage and Novel Cell Technology, School of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng, 252000, China.
Background: Localized surface plasmon resonance (LSPR) sensor has drawn continuous attention to application of the detection of antibody, protein, virus, and bacteria. However, natural recognition molecules, such as antibody, which possess some properties, including low thermal stability, complicated operation and high price, uncontrollability of length and size and a tendency to accumulate easily on the surface of chip to reduce the sensitive of method. Furthermore, common blocking agents are not suitable for development of novel biosensors.
View Article and Find Full Text PDFAnal Chim Acta
January 2025
School of Forensic Medicine, China Medical University, No.77 Puhe Road, Shenyang, Liaoning, 110122, China. Electronic address:
The detection of biomarkers is crucial for assessing disease status and progression. Uric acid (UA), a common biomarker in body fluids, plays an important role in the diagnosis and monitoring of conditions such as hyperuricemia, chronic kidney disease, and cardiovascular disease. However, the low concentration of UA in non-invasive body fluids, combined with numerous interfering substances, makes its detection challenging.
View Article and Find Full Text PDFJ Hazard Mater
January 2025
Fujian Provincial Key Laboratory for Coastal Ecology and Environmental Studies, State Key Laboratory of Marine Environmental Science, Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystem, College of the Environment and Ecology, Xiamen University, Xiamen 361102, China. Electronic address:
Predicting nanoplastic bioaccumulation and toxicity using process-based models is challenging due to the difficulties in tracing them at low concentrations. This study investigates the size-dependent effects of nanoplastic exposure on Daphnia magna using a toxicokinetic-toxicodynamic (TKTD) model. Palladium-doped fluorescent nanoplastics in three sizes (30-nm, 66-nm, 170-nm) were tested at two numeric exposure concentrations.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
International Advanced Research Centre for Powder Metallurgy and New Materials (ARCI), IIT M Research Park, Chennai 600113, India.
The MgSb-based layered compounds exhibit exceptional thermoelectric properties over a wide temperature range and possess the potential to supplant traditional BiTe modules with reliable and economical MgSb-based thermoelectric devices, contingent upon the availability of a complementary p-type MgSb material with high thermoelectric efficiency comparable to that of n-type MgSb. We provide a simpler method involving the codoping of monovalent atoms (K and Na) at the Mg site of the MgSb lattice to improve the thermoelectric performance of p-type MgSb. K-Na codoping results in a peak power factor of around 0.
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