To test the ultra-deep conic surface in wide-field optical systems, a catadioptric null test method is researched in this paper. Equations of infinite conjugate null test system are established and solved using optical path length. The numeric results of a self-aligning mirror's shapes are fitted by coefficients and validation is done in optical design software. The rms wavefront error is 0.0019λ (λ=632.8 nm) in the example fitted by five coefficients. Furthermore, by adjusting spherical aberration distributions, an all-spherical finite conjugate null test system is designed, whose rms wavefront error is 0.0309λ. The test methods in this paper have been proven to be adaptive to many other similar ultra-deep surfaces, even with higher orders.
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http://dx.doi.org/10.1364/AO.52.004738 | DOI Listing |
J Educ Health Promot
November 2024
Department of Child Health Nursing, Nitte (Deemed to be University), Nitte Usha Institute of Nursing Sciences (NUINS), Mangalore, Karnataka, India.
Background: Electronic devices like laptops, desktops, and cell phones are now essential in modern life, especially for students, due to their convenience and time-saving benefits. However, concerns about social issues related to prolonged use, particularly among kids and teenagers, have arisen. This study aimed to evaluate the efficacy of an exercise package in mitigating symptoms of eye and neck strain among adolescents who are regular users of electronic devices.
View Article and Find Full Text PDFACS Med Chem Lett
January 2025
Sustainable Chemistry for Metals and Molecules, Department of Chemistry, KU Leuven, Leuven 3000, Belgium.
Cruzipain (CZP) is an essential cysteine protease of , the etiological agent of Chagas disease, and a promising druggable target. To date, no CZP inhibitors have reached clinical use, with research efforts mostly hampered by insufficient potency, limited target selectivity or lack of bioactivity translation from the isolated enzyme to the parasite in cellular environments. In this study, we report the design of , a 1,2,3-triazole-based targeted covalent inhibitor with nanomolar potency (IC = 28 nM) and null inhibition of human cathepsin L.
View Article and Find Full Text PDFEmergencias
December 2024
Department of Emergency Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seúl, República de Corea. Department of Digital Health, SAIHST, Sungkyunkwan University, Seúl, República de Corea.
Objective: To develop a Metabolic Derangement Score (MDS) based on parameters available after initial testing and assess the score's ability to predict survival after out-of hospital cardiac arrest (OHCA) and the likely usefulness of extracorporeal life support (ECLS).
Methods: A total of 5100 cases in the Korean Cardiac Arrest Research Consortium registry were included. Patients' mean age was 67 years, and 69% were men.
Acta Otolaryngol
January 2025
Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Kyung Hee University, Seoul, Korea.
Background: The Canalith Repositioning Maneuver (CRM) is often ineffective for persistent geotropic direction-changing positional nystagmus (DCPN). In these cases, determining the lesion side can be challenging, as the null plane side and the side with stronger nystagmus on the roll test are frequently opposite.
Objectives: This study investigates whether the low therapeutic efficacy of CRM in persistent DCPN could be attributed to incorrect determination of the lesion side.
J Child Lang
January 2025
The Graduate Center, City University of New York, New York City, NY, USA.
This study will investigate how children acquire the option to drop the subject of a sentence, or null subjects (e.g., "Tickles me" instead of "He tickles me").
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