This article considers the process of ethical review of research on human subjects at a very large multinational consumer products company. The commercial context of this research throws up unique challenges and opportunities that make the ethics of the process of oversight distinct from mainstream medical research. Reflection on the justification of governance processes sheds important, contrasting light on the ethics of governance of other forms and context of research.
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http://dx.doi.org/10.1111/bioe.12040 | DOI Listing |
Front Cell Dev Biol
January 2025
Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Liver cancer is a leading cause of cancer-related deaths worldwide, highlighting the need for innovative approaches to understand its complex biology and develop effective treatments. While traditional animal models have played a vital role in liver cancer research, ethical concerns and the demand for more human-relevant systems have driven the development of advanced models. Spheroids and organoids have emerged as powerful tools due to their ability to replicate tumor microenvironment and facilitate preclinical drug development.
View Article and Find Full Text PDFInt J Biochem Mol Biol
December 2024
Gene Expression and Signaling Lab, Department of Zoology, Mahatma Gandhi Central University Motihari 845401, Bihar, India.
Edible oils and ghee are vital parts of our daily culinary practices. In recent years, owing to heightened demand in the domestic and global markets, consistent reports regarding the adulteration of edible oils and ghee with substandard ingredients have been reported. Adulteration in edible oils is widespread, with distinctive contaminants, including cottonseed, mineral, and lower-cost oils like palm olein.
View Article and Find Full Text PDFFront Vet Sci
January 2025
Clinic for Horses, Department of Surgery and Orthopedics, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
The skills necessary to perform diagnostic perineural anesthesia in equids belongs to one of the Day One Competences of a veterinarian, so every veterinary graduate should be able to perform them correctly. For logistical, hygienic and ethical reasons, practical exercises on cadaver limbs are not accessible to all students. Two equine distal limb simulators were developed and evaluated as an additional instructional tool to train the required skills.
View Article and Find Full Text PDFJ Educ Health Promot
December 2024
Student Research Committee, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Ethical conflict among nurses has a significant impact on their health and the quality of nursing care. The lack of specific ethical and legal signs and obstacles for reporting ethical conflict in nurses has made diagnosis and the management of its negative consequences difficult. This study aims to develop a valid, reliable, evidence-based instrument to assess the ethical conflict of nurses in the sociocultural and managerial context of Iran.
View Article and Find Full Text PDFCureus
December 2024
General Surgery, Hayatabad Medical Complex Peshawar, Peshawar, PAK.
Objective: The study aimed to investigate the rate of conversion from laparoscopic cholecystectomy (LC) to open cholecystectomy (OC) in our population and determine the potential risk factors associated with it. Understanding these factors helps surgeons predict complex cases and plan surgeries, reducing patient risks and improving outcomes.
Methodology: A cross-sectional observational study was conducted from June 1, 2022, to May 31, 2023, at Hayatabad Medical Complex, Peshawar, on 349 patients undergoing elective LC.
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