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A ratiometric fluorescent dye for the detection of glutathione in live cells and liver cancer tissue. | LitMetric

A ratiometric fluorescent dye for the detection of glutathione in live cells and liver cancer tissue.

Chem Commun (Camb)

Department of Chemistry and MedChem Program, Life Sciences Institute, National University of Singapore, 3 Science Drive 3, Singapore 117543.

Published: August 2013

AI Article Synopsis

Article Abstract

A novel ratiometric biothiol probe Glutathione Green was developed. It allows quantitative measurement of glutathione in cell extracts and direct visualization of changes in glutathione levels in live cells. Remarkably, this is the first reported biothiol probe which can detect the carcinoma region of liver tissue based on the differences in the glutathione level.

Download full-text PDF

Source
http://dx.doi.org/10.1039/c3cc43480jDOI Listing

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