Functionalized liposome purification via Liposome Extruder Purification (LEP).

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Department of Chemical and Biomolecular Engineering, University of Notre Dame, 165 Fitzpatrick Hall, Notre Dame, IN 46556-5637, USA.

Published: September 2013

Liposome Extruder Purification (LEP) allows for the rapid purification of diverse liposome formulations using the same extrusion apparatus employed during liposome formation. The LEP process provides a means for purifying functionalized liposomes from non-conjugated drug or protein contaminants with >93% liposome recovery and >93% contaminant removal in a single step.

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http://dx.doi.org/10.1039/c3an00680hDOI Listing

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