A mother and daughter with an interstitial deletion of the chromosome segment 21q11 to 21q21.3 have similar minor dysmorphism and mild mental retardation. These two patients are compared to others in the literature with deletion of the same region of chromosome 21. Molecular analysis of DNA from our patients localizes the DNA segments D21S1, D21S11, D21S8, and D21S22 within the deleted region.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1399-0004.1990.tb03525.x | DOI Listing |
Publication Analysis
Top Keywords
interstitial deletion
8
familial interstitial
4
deletion long
4
long arm
4
arm chromosome
4
chromosome mother
4
mother daughter
4
daughter interstitial
4
deletion chromosome
4
chromosome segment
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!